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AGO1 gene

Known as: EUKARYOTIC TRANSLATION INITIATION FACTOR 2C, SUBUNIT 1, AGO1, argonaute 1 
This gene is involved in RNA binding and gene silencing.
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Dieter Edbauer,1,4,* Joel R. Neilson,2 Kelly A. Foster,1 Chi-Fong Wang,1 Daniel P. Seeburg,1 Matthew N. Batterton,1 Tomoko Tada,1… Expand
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Highly Cited
2008
Highly Cited
2008
MicroRNAs (miRNAs) regulate gene expression at the posttranscriptional level in the cytoplasm, but recent findings suggest… Expand
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Highly Cited
2006
Highly Cited
2006
Arabidopsis ARGONAUTE1 (AGO1) encodes the RNA slicer enzyme of the microRNA (miRNA) pathway and is regulated by miR168-programmed… Expand
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Highly Cited
2005
Highly Cited
2005
RNA interference (RNAi) is an important means of eliminating mRNAs, but the intracellular location of RNA-induced silencing… Expand
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Highly Cited
2004
Highly Cited
2004
Argonaute proteins associate with small RNAs that guide mRNA degradation, translational repression, or a combination of both. The… Expand
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Highly Cited
2004
Highly Cited
2004
Fragile X syndrome is caused by a loss of expression of the fragile X mental retardation protein (FMRP). FMRP is a selective RNA… Expand
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Highly Cited
2004
Highly Cited
2004
RNA interference (RNAi) is a widespread silencing mechanism that acts at both the posttranscriptional and transcriptional levels… Expand
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Highly Cited
2004
Highly Cited
2004
In mammalian cells, both microRNAs (miRNAs) and small interfering RNAs (siRNAs) are thought to be loaded into the same RNA… Expand
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Highly Cited
2000
Highly Cited
2000
Introduction of transgene DNA may lead to specific degradation of RNAs that are homologous to the transgene transcribed sequence… Expand
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Highly Cited
1998
Highly Cited
1998
An allelic series of the novel argonaute mutant (ago1‐1 to ago1‐6) of the herbaceous plant Arabidopsis thaliana has been isolated… Expand
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