Semantic Scholar uses AI to extract papers important to this topic.
The functional roles of SNPs within the 8q24 gene desert in the cancer phenotype are not yet well understood. Here, we report… Expand The 8q24 gene desert contains risk loci for multiple epithelial cancers, including colon, breast, and prostate. Recent evidence… Expand Previous studies have identified multiple loci on 8q24 associated with prostate cancer risk. We performed a comprehensive… Expand In a genome-wide association study to identify loci associated with colorectal cancer (CRC) risk, we genotyped 555,510 SNPs in 1… Expand We conducted a genome-wide SNP association study on 1,803 urinary bladder cancer (UBC) cases and 34,336 controls from Iceland and… Expand Recently, common variants on human chromosome 8q24 were found to be associated with prostate cancer risk. While conducting a… Expand Using a multistage genetic association approach comprising 7,480 affected individuals and 7,779 controls, we identified markers… Expand Prostate cancer is the most prevalent noncutaneous cancer in males in developed regions, with African American men having among… Expand After the recent discovery that common genetic variation in 8q24 influences inherited risk of prostate cancer, we genotyped 2,973… Expand A whole-genome admixture scan in 1,597 African Americans identified a 3.8 Mb interval on chromosome 8q24 as significantly… Expand