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E 3123

Known as: E-3123, E3123 
National Institutes of Health

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Broader (1)

4-(2-succinimidoethylthio)phenyl 4-guanidinobenzoate

Papers overview

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1997
1997
Distribution of a Synthetic Protease Inhibitor in Rat Pancreatic Acini After Supramaximal Secretagogue Stimulation
Protease inhibitors may have a beneficial effect in acute pancreatitis. The effects of E3123, a new low molecular weight protease… 
1995
1995
Protective effects of prophylaxis with a protease inhibitor and a free radical scavenger against a temporary ischemia model of pancreatitis.
OBJECTIVE To evaluate the protective effects of combined prophylaxis with 4-sulfamoylphenyl, 4-guanidinobenzoate methanesulfonate… 
1994
1994
Effect of short-term pancreatico-biliary duct obstruction with intraductal hypertension on subcellular organelle fragility and pancreatic adenylate energy metabolism in rats: protective effect of a…
Blockage of the rat pancreatico-biliary duct (PBDO) for 4 hours and secretin infusion (0.2 CU [Clinical Unit]/kg/hr) caused… 
1994
1994
Monitoring serum tryptic activity and effect of trypsin inhibitor on rat acute pancreatitis.
The effect of a novel synthetic trypsin inhibitor, 4-(2-succinimidoethylthio)-phenyl 4-guanidinobenzoate methanesulfonate (E3123… 
1994
1994
Intracellular action of an exogenous low-molecular-weight synthetic protease inhibitor, E3123, in cerulein-induced acute pancreatitis in rats
SummaryThe intracellular distribution and action of a new synthetic protease inhibitor, E3123, were studied in cerulein-induced… 
1993
1993
Protective effect of a cephalosporin, Shiomarin, plus a new potent protease inhibitor, E3123, on rat taurocholate‐induced pancreatitis
Abstract The role of infectious factors in the pathogenesis of acute pancreatitis and the protective effect of combined therapy… 
1992
1992
Acute cytotoxic effect of cyclosporin A on pancreatic acinar cells in rats. Protective effect of the synthetic protease inhibitor E3123.
This study was designed to evaluate the acute toxic effects of cyclosporin A on the exocrine pancreas and the protective effects… 
1990
1990
E-3123, a new synthetic protease inhibitor, protects against deoxycholic acid-induced acute pancreatitis in dogs.
The effects of intravenous infusion of 4-(2-succinimidoethylthio)phenyl 4-guanidinobenzoate (E-3123), a new synthetic protease… 
1989
1989
Kinetic study on the mechanism of inhibition of trypsin and trypsin-like enzymes by p-guanidinobenzoate ester.
It was found that [4-(2-succinimidoethylthio)phenyl 4-guanidinobenzoate]methanesulfonate (E-3123) inhibits trypsin, thrombin and… 
1988
1988
[Effects of E-3123, a new protease inhibitor, on several protease activities and on experimental acute pancreatitis].
4-(2-Succinimidoethylthio) phenyl 4-guanidinobenzoate (E-3123) potently inhibited trypsin, plasmin and thrombin with IC50 values… 
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