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Disulfiram

Known as: Disulfiram [Chemical/Ingredient], TTD, Disulfide, Tetraethylthiuram 
A carbamoyl derivate used in the treatment of alcoholism. Disulfiram irreversibly inhibits acetaldehyde dehydrogenase that oxidizes the ethanol… 
National Institutes of Health

Papers overview

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Highly Cited
2020
Highly Cited
2020
Cytosolic sensing of pathogens and damage by myeloid and barrier epithelial cells assembles large complexes called inflammasomes… 
Highly Cited
2017
Highly Cited
2017
Cancer incidence is rising and this global challenge is further exacerbated by tumour resistance to available medicines. A… 
Highly Cited
2013
Highly Cited
2013
The combination of a chemotherapeutic drug with a multidrug resistance (MDR) modulator has emerged as a promising strategy for… 
Highly Cited
2011
Highly Cited
2011
Background:Previous studies indicate that disulfiram (DS), an anti-alcoholism drug, is cytotoxic to cancer cell lines and… 
Review
2006
Review
2006
Abstract: For more than 55 years, disulfiram has been approved by the Food and Drug Administration for the treatment of alcohol… 
Highly Cited
2006
Highly Cited
2006
Disulfiram (DSF), a member of the dithiocarbamate family capable of binding copper and an inhibitor of aldehyde dehydrogenase, is… 
Highly Cited
1993
Highly Cited
1993
SODIUM-RICH rocks of trondhjemite–tonalite–dacite (TTD) or –granodiorite (TTG) suites form much of Precambrian continental crust1… 
Review
1992
Review
1992
  • B. Johansson
  • Acta Psychiatrica Scandinavica Supplementum
  • 1992
  • Corpus ID: 23832065
After ingestion, disulfiram (DSF) is rapidly converted, probably in the stomach, to its bis (diethyldithiocarbamato) copper… 
Highly Cited
1986
Highly Cited
1986
We conducted a controlled, blinded, multicenter study of disulfiram treatment of alcoholism in 605 men randomly assigned to 250… 
Highly Cited
1972
Highly Cited
1972
1. The ;xanthine oxidase' activity of rat liver supernatant, most of which behaves as an NAD(+)-dependent dehydrogenase (type D…