Diethyldithiocarbamate

A sulfhydryl-containing carbamate that is the primary in vivo metabolite of disulfiram. Diethyldithiocarbamate chelates zinc, thereby inhibiting… (More)

Topic mentions per year

Topic mentions per year

1941-2018
05019412017

Papers overview

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Highly Cited
2003
Highly Cited
2003
Tetrahydrobiopterin (BH4) serves as a critical co-factor for the endothelial nitric-oxide synthase (eNOS). A deficiency of BH4… (More)
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Highly Cited
2001
Highly Cited
2001
The present study characterized the biochemical pathways responsible for superoxide (O(2)(-.)) production in different regions of… (More)
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Highly Cited
1999
Highly Cited
1999
Although a burst of oxidants has been well described with reperfusion, less is known about the oxidants generated by the highly… (More)
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1995
1995
This investigation was undertaken to explain the possible, mechanism(s) of protection by diethyldithiocarbamate (DDTC) against… (More)
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Highly Cited
1995
Highly Cited
1995
Identifying selective inhibitors of cytochrome P450 isoforms is a useful tool in defining the role of individual cytochrome P450s… (More)
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Highly Cited
1994
Highly Cited
1994
A variety of chemicals, including triacetyloleandomycin (TAO), alpha-naphthoflavone (ANF), and diethyldithiocarbamate (DDC), are… (More)
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Highly Cited
1991
Highly Cited
1991
Few nonphagocytic cells are known to generate reactive oxygen intermediates. Based on horseradish peroxidase-dependent, catalase… (More)
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Highly Cited
1991
Highly Cited
1991
The role of human cytochrome P-450 IIE1 (P-450 IIE1) in the oxidation of a number of suspect carcinogens was examined by using a… (More)
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Highly Cited
1984
Highly Cited
1984
During renal ischemia, ATP is degraded to hypoxanthine. When xanthine oxidase converts hypoxanthine to xanthine in the presence… (More)
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Highly Cited
1976
Highly Cited
1976
Superoxide dismutase was assayed by a method which takes advantage of the inhibitory action of superoxide dismutase (or tissues… (More)
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