Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Diablo Homolog, Mitochondrial

Known as: DIABLO, Smac, Direct IAP-Binding Protein with Low pI 
Diablo homolog, mitochondrial (239 aa, ~27 kDa) is encoded by the human DIABLO gene. This protein plays a role in the activation of caspase-dependent… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
A plethora of apoptotic stimuli converge on the mitochondria and affect their membrane integrity. As a consequence, multiple… Expand
  • figure 1
  • table 1
  • figure 2
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Survivin is a member of the inhibitor of apoptosis protein (IAP) family that has been implicated in both apoptosis inhibition and… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Inhibitor of apoptosis (IAP) proteins inhibit caspases, a function counteracted by IAP antagonists, insect Grim, HID, and Reaper… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Recent reports suggest that a cross-talk exists between apoptosis pathways mediated by mitochondria and cell death receptors. In… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
During apoptosis, Smac (secondmitochondria-derived activator ofcaspases)/DIABLO, an IAP (inhibitor of apoptosis protein)-binding… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
X-linked inhibitor-of-apoptosis protein (XIAP) interacts with caspase-9 and inhibits its activity, whereas Smac (also known as… Expand
Is this relevant?
Review
2001
Review
2001
Cellular stresses, such as growth factor deprivation, DNA damage or oncogene expression, lead to stabilization and activation of… Expand
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Smac/DIABLO is a mitochondrial protein that potentiates some forms of apoptosis, possibly by neutralizing one or more members of… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Apoptosis (programmed cell death), an essential process in the development and homeostasis of metazoans, is carried out by… Expand
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Smac/DIABLO is a mitochondrial protein that is released along with cytochrome c during apoptosis and promotes cytochrome c… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?