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Deoxyribonucleotide Triphosphate

Known as: dNTP 
A nucleotide comprised of either a purine or pyrimidine nitrogenous base bound to a deoxyribose sugar esterified with three phosphate groups. These… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease
The maintenance of a healthy deoxyribonucleotide triphosphate (dNTP) pool is critical for the proper replication and repair of… Expand
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Review
2004
Review
2004
Physiological concentrations of purines and pyrimidines
  • T. Traut
  • Molecular and Cellular Biochemistry
  • 2004
    • Corpus ID: 25417169
The concentrations of bases, nucleosides, and nucleosides mono-, di- and tri-phosphate are compared for about 600 published… Expand
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Highly Cited
2001
Highly Cited
2001
Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy
The mitochondrial deoxyribonucleotide (dNTP) pool is separated from the cytosolic pool because the mitochondria inner membrane is… Expand
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Highly Cited
1998
Highly Cited
1998
Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance.
A combinatorial disulfide cross-linking strategy was used to prepare a stalled complex of human immunodeficiency virus-type 1… Expand
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Highly Cited
1998
Highly Cited
1998
A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools.
In Saccharomyces cerevisiae, MEC1 and RAD53 are essential for cell growth and checkpoint function. Their essential role in growth… Expand
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Review
1997
Review
1997
DNA glycosylases in the base excision repair of DNA.
A wide range of cytotoxic and mutagenic DNA bases are removed by different DNA glycosylases, which initiate the base excision… Expand
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Highly Cited
1996
Highly Cited
1996
PCR fidelity of pfu DNA polymerase and other thermostable DNA polymerases.
The replication fidelities of Pfu, Taq, Vent, Deep Vent and UlTma DNA polymerases were compared using a PCR-based forward… Expand
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Highly Cited
1994
Highly Cited
1994
Convenient single-step, one tube purification of PCR products for direct sequencing.
Structural alterations of the apolipoprotein E (apo E) are known to influence the lipid metabolism. The three most common… Expand
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Highly Cited
1990
Highly Cited
1990
Effects of primer-template mismatches on the polymerase chain reaction: human immunodeficiency virus type 1 model studies.
We investigated the effects of various primer-template mismatches on DNA amplification of an HIV-1 gag region by the polymerase… Expand
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Highly Cited
1988
Highly Cited
1988
Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.
We have devised a simple and efficient cDNA cloning strategy that overcomes many of the difficulties encountered in obtaining… Expand
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