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Deoxyribonucleotide Triphosphate
Known as:
dNTP
A nucleotide comprised of either a purine or pyrimidine nitrogenous base bound to a deoxyribose sugar esterified with three phosphate groups. These…
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National Institutes of Health
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Papers overview
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Highly Cited
2002
Highly Cited
2002
The M184V Mutation Reduces the Selective Excision of Zidovudine 5′-Monophosphate (AZTMP) by the Reverse Transcriptase of Human Immunodeficiency Virus Type 1
P. Boyer
,
S. Sarafianos
,
E. Arnold
,
S. Hughes
Journal of Virology
2002
Corpus ID: 23422363
ABSTRACT The M184V mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) causes resistance to…
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Highly Cited
2000
Highly Cited
2000
Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase.
Falguni. S. Shah
,
Kenneth Curr
,
+4 authors
V. Prasad
Journal of Biological Chemistry
2000
Corpus ID: 35535024
Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) variants with the K65R or L74V substitution display…
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Highly Cited
2000
Highly Cited
2000
Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast.
M. P. Longhese
,
V. Paciotti
,
H. Neecke
,
G. Lucchini
Genetics
2000
Corpus ID: 19240562
A complex network of surveillance mechanisms, called checkpoints, interrupts cell cycle progression when damage to the genome is…
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Highly Cited
1998
Highly Cited
1998
Deoxyribonucleoside Triphosphate Pool Imbalances In Vivo Are Associated with an Increased Retroviral Mutation Rate
J. G. Julias
,
V. Pathak
Journal of Virology
1998
Corpus ID: 13602766
ABSTRACT Deoxyribonucleoside triphosphate (dNTP) pool imbalances are associated with an increase in the rate of misincorporation…
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Highly Cited
1998
Highly Cited
1998
DNA polymerase β : effects of gapped DNA substrates on dNTP specificity, fidelity, processivity and conformational changes1
J. Ahn
,
V. Kraynov
,
X. Zhong
,
B. G. Werneburg
,
M. Tsai
1998
Corpus ID: 1575342
Pre-steady-state kinetic analysis was used to compare the catalytic properties of DNA polymerase β (Pol β) for single-base…
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Highly Cited
1990
Highly Cited
1990
Genomic walking and sequencing by oligo-cassette mediated polymerase chain reaction.
Andre Rosenthal
,
D. S. Jones
Nucleic Acids Research
1990
Corpus ID: 42614992
Recently, a method named inverse PCR has been described by which genomic DNA sequences adjacent to a known (sequenced) locus can…
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Highly Cited
1988
Highly Cited
1988
Primary structure of T4 DNA polymerase. Evolutionary relatedness to eucaryotic and other procaryotic DNA polymerases.
Eleanor K. SpicerSg
,
John RushSY
,
Claire FungSII
,
L. Reha-Krantz
,
Jim D. KaramSS
,
William H. KonigsbergS
Journal of Biological Chemistry
1988
Corpus ID: 2355484
Highly Cited
1982
Highly Cited
1982
The role of DNA polymerase in base substitution mutagenesis on non-instructional templates.
Bernard S. Strauss
,
Samuel D. Rabkin
,
Daphna Sagher
,
Peter D. Moore
Biochimie
1982
Corpus ID: 4916392
Highly Cited
1979
Highly Cited
1979
Involvement of eucaryotic deoxyribonucleic acid polymerases alpha and gamma in the replication of cellular and viral deoxyribonucleic acid.
H. Krokan
,
P. Schaffer
,
M. DePamphilis
Biochemistry
1979
Corpus ID: 32864983
In an effort to identify the deoxyribonucleic acid (DNA) polymerase activities responsible for mammalian viral and cellular DNA…
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Highly Cited
1978
Highly Cited
1978
Effect of 2',3'-dideoxythymidine-5'-triphosphate on HeLa cell in vitro DNA synthesis: evidence that DNA polymerase alpha is the only polymerase required for cellular DNA replication.
M. Waqar
,
M. J. Evans
,
J. Huberman
Nucleic Acids Research
1978
Corpus ID: 20506435
We have studied the effects of the nucleotide analogue, 2',3'-dideoxythymidine-5'-triphosphate (ddTTP) on replicative DNA…
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