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Deoxyribonucleotide Triphosphate

Known as: dNTP 
A nucleotide comprised of either a purine or pyrimidine nitrogenous base bound to a deoxyribose sugar esterified with three phosphate groups. These… 
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
The M184V Mutation Reduces the Selective Excision of Zidovudine 5′-Monophosphate (AZTMP) by the Reverse Transcriptase of Human Immunodeficiency Virus Type 1
ABSTRACT The M184V mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) causes resistance to… 
Highly Cited
2000
Highly Cited
2000
Differential influence of nucleoside analog-resistance mutations K65R and L74V on the overall mutation rate and error specificity of human immunodeficiency virus type 1 reverse transcriptase.
Human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) variants with the K65R or L74V substitution display… 
Highly Cited
2000
Highly Cited
2000
Checkpoint proteins influence telomeric silencing and length maintenance in budding yeast.
A complex network of surveillance mechanisms, called checkpoints, interrupts cell cycle progression when damage to the genome is… 
Highly Cited
1998
Highly Cited
1998
Deoxyribonucleoside Triphosphate Pool Imbalances In Vivo Are Associated with an Increased Retroviral Mutation Rate
ABSTRACT Deoxyribonucleoside triphosphate (dNTP) pool imbalances are associated with an increase in the rate of misincorporation… 
Highly Cited
1998
Highly Cited
1998
DNA polymerase β : effects of gapped DNA substrates on dNTP specificity, fidelity, processivity and conformational changes1
Pre-steady-state kinetic analysis was used to compare the catalytic properties of DNA polymerase β (Pol β) for single-base… 
Highly Cited
1990
Highly Cited
1990
Genomic walking and sequencing by oligo-cassette mediated polymerase chain reaction.
Recently, a method named inverse PCR has been described by which genomic DNA sequences adjacent to a known (sequenced) locus can… 
Highly Cited
1988
Highly Cited
1988
Primary structure of T4 DNA polymerase. Evolutionary relatedness to eucaryotic and other procaryotic DNA polymerases.
Highly Cited
1982
Highly Cited
1982
The role of DNA polymerase in base substitution mutagenesis on non-instructional templates.
Highly Cited
1979
Highly Cited
1979
Involvement of eucaryotic deoxyribonucleic acid polymerases alpha and gamma in the replication of cellular and viral deoxyribonucleic acid.
In an effort to identify the deoxyribonucleic acid (DNA) polymerase activities responsible for mammalian viral and cellular DNA… 
Highly Cited
1978
Highly Cited
1978
Effect of 2',3'-dideoxythymidine-5'-triphosphate on HeLa cell in vitro DNA synthesis: evidence that DNA polymerase alpha is the only polymerase required for cellular DNA replication.
We have studied the effects of the nucleotide analogue, 2',3'-dideoxythymidine-5'-triphosphate (ddTTP) on replicative DNA… 
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