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Defensins

Known as: Defensins [Chemical/Ingredient], defensin 
Family of antimicrobial peptides that have been identified in humans, animals, and plants. They are thought to play a role in host defenses against… Expand
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Antimicrobial peptides are important effectors of innate immunity throughout the plant and animal kingdoms. In the mammalian… Expand
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Highly Cited
2005
Highly Cited
2005
The pathogenesis of Crohn's disease (CD), an idiopathic inflammatory bowel disease, is attributed, in part, to intestinal… Expand
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Highly Cited
2004
Highly Cited
2004
Background: Mutations in NOD2, a putative intracellular receptor for bacterial peptidoglycans, are associated with a subset of… Expand
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Review
2002
Review
2002
During the past year, novel beta-defensins of mice and men have been identified, together with a novel defensin subfamily (the… Expand
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Review
2002
Review
2002
Mammalian defensins are small, cationic, antimicrobial peptides encoded by the host that are considered to be important… Expand
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Highly Cited
1999
Highly Cited
1999
Defensins contribute to host defense by disrupting the cytoplasmic membrane of microorganisms. This report shows that human beta… Expand
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Highly Cited
1999
Highly Cited
1999
Positively charged antimicrobial peptides with membrane-damaging activity are produced by animals and humans as components of… Expand
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Highly Cited
1999
Highly Cited
1999
Precursors of alpha-defensin peptides require activation for bactericidal activity. In mouse small intestine, matrilysin… Expand
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Review
1993
Review
1993
Defensins are antimicrobial and cytotoxic peptides that contain 29-35 amino acid residues, including six invariant cysteines… Expand
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Highly Cited
1986
Highly Cited
1986
Human neutrophils contain a family of microbicidal peptides known as defensins. One of these defensins, human neutrophil peptide… Expand
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