Defensins

Known as: Defensins [Chemical/Ingredient], defensin 
Family of antimicrobial peptides that have been identified in humans, animals, and plants. They are thought to play a role in host defenses against… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
Antimicrobial peptides are important effectors of innate immunity throughout the plant and animal kingdoms. In the mammalian… (More)
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Highly Cited
2005
Highly Cited
2005
The pathogenesis of Crohn's disease (CD), an idiopathic inflammatory bowel disease, is attributed, in part, to intestinal… (More)
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Review
2004
Review
2004
Defensins are endogenous, cysteine-rich antimicrobial peptides that contribute to host defence against bacterial, fungal and… (More)
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Review
2002
Review
2002
During the past year, novel beta-defensins of mice and men have been identified, together with a novel defensin subfamily (the… (More)
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Highly Cited
2001
Highly Cited
2001
Defensins, antimicrobial peptides of the innate immune system, protect human mucosal epithelia and skin against microbial… (More)
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Highly Cited
1999
Highly Cited
1999
Defensins contribute to host defense by disrupting the cytoplasmic membrane of microorganisms. This report shows that human beta… (More)
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Highly Cited
1999
Highly Cited
1999
Positively charged antimicrobial peptides with membrane-damaging activity are produced by animals and humans as components of… (More)
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Highly Cited
1997
Highly Cited
1997
A human bronchial xenograft model was used to characterize the molecular basis for the previously described defect in bacterial… (More)
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Review
1993
Review
1993
Defensins are antimicrobial and cytotoxic peptides that contain 29-35 amino acid residues, including six invariant cysteines… (More)
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Highly Cited
1985
Highly Cited
1985
We extracted a granule-rich sediment from normal human neutrophils and subjected it to chromatographic, electrophoretic, and… (More)
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