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Defensins

Known as: Defensins [Chemical/Ingredient], defensin 
Family of antimicrobial peptides that have been identified in humans, animals, and plants. They are thought to play a role in host defenses against… 
National Institutes of Health

Related topics

Related topics

33 relations

Narrower (16)

AdDLP protein, Anaeromyxobacter dehalogenansDEFL202 protein, ArabidopsisDm-AMP1 protein, Dahlia merckiiPDF1.2 protein, Arabidopsis

Broader (2)

Anti-Infective AgentsAntibiotics
DEFA8P geneDEFB103A geneDEFB104A geneDEFB105A gene

Papers overview

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Highly Cited
2009
Highly Cited
2009
Topical calcineurin inhibitors compromise stratum corneum integrity, epidermal permeability and antimicrobial barrier function
Please cite this paper as: Topical calcineurin inhibitors compromise stratum corneum integrity, epidermal permeability and… 
Review
2007
Review
2007
Defensins and cathelicidins in gastrointestinal infections
Purpose of review To review recently published studies presenting novel and relevant information on antimicrobial peptides in… 
Highly Cited
2006
Highly Cited
2006
θ-Defensins Prevent HIV-1 Env-mediated Fusion by Binding gp41 and Blocking 6-Helix Bundle Formation*
Retrocyclin-1, a θ-defensin, protects target cells from human immunodeficiency virus, type 1 (HIV-1) by preventing viral entry… 
Highly Cited
2005
Highly Cited
2005
Inhibition of pathologic retinal neovascularization by α-defensins
Proliferative retinopathies, such as those complicating prematurity and diabetes, are major causes of blindness. A prominent… 
Highly Cited
2005
Highly Cited
2005
Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity.
Alpha-defensins are abundant antimicrobial peptides in polymorphonuclear leukocytes and play an important role in innate immunity… 
Highly Cited
2003
Highly Cited
2003
Quantitative interactions between cryptdin-4 amino terminal variants and membranes
Review
2001
Review
2001
Defensins – innate immunity at the epithelial frontier
Physical barrier function was formerly believed to play the major role in mucosal protection against luminal bacteria. This view… 
Highly Cited
2000
Highly Cited
2000
Endonuclease activity in lipocalins.
Several lipocalins contain conserved amino acid sequences similar to the phosphodiester bond cleavage domain of sugar non… 
Highly Cited
1999
Highly Cited
1999
Epithelial defensins impair adenoviral infection: implication for adenovirus-mediated gene therapy.
Epithelial cells have been to participate actively in host defense by producing small cationic peptides called defensins. To… 
Highly Cited
1999
Highly Cited
1999
Reduced antimicrobial peptide expression in human burn wounds.
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