G. Nair

Publications542
h-index79
Citations23,270
Highly Influential Citations1,178
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Evidence for several waves of global transmission in the seventh cholera pandemic
TLDR
It is shown here that the seventh pandemic has spread from the Bay of Bengal in at least three independent but overlapping waves with a common ancestor in the 1950s, and several transcontinental transmission events are identified.
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Emergence of a unique O3:K6 clone of Vibrio parahaemolyticus in Calcutta, India, and isolation of strains from the same clonal group from Southeast Asian travelers arriving in Japan
TLDR
The results suggest that this unique O3:K6 clone may have become prevalent not only in Calcutta but also in Southeast Asian countries very recently.
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Rapid Method for Species-Specific Identification ofVibrio cholerae Using Primers Targeted to the Gene of Outer Membrane Protein OmpW
TLDR
A one-step multiplex PCR assay for the simultaneous amplification of ompW and ctxAgenes should be of considerable value in the screening of both toxigenic and nontoxigenic V. cholerae strains of clinical as well as environmental origin.
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Critical Factors Influencing the Occurrence of Vibrio cholerae in the Environment of Bangladesh
TLDR
The results of environmental sampling and analysis of the environmental and clinical data have revealed significant correlations of water temperature, water depth, rainfall, conductivity, and copepod counts with the occurrence of cholera toxin-producing bacteria (presumably V. cholerae).
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A Multicentre Study of Shigella Diarrhoea in Six Asian Countries: Disease Burden, Clinical Manifestations, and Microbiology
TLDR
Shigella appears to be more ubiquitous in Asian impoverished populations than previously thought, and antibiotic-resistant strains of different species and serotypes have emerged.
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Comparative genomics reveals mechanism for short-term and long-term clonal transitions in pandemic Vibrio cholerae
TLDR
Based on the comparative genomics, it is concluded that V. cholerae undergoes extensive genetic recombination via lateral gene transfer, and, therefore, genome assortment, not serogroup, should be used to define pathogenic V.cholerae clones.
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Evolution of new variants of Vibrio cholerae O1.
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Seasonal epidemics of cholera inversely correlate with the prevalence of environmental cholera phages.
TLDR
The data support the conclusion that cholERA phages can influence cholera seasonality and may also play a role in emergence of new V. cholerae pandemic serogroups or clones.
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Development and evaluation of a multiplex PCR assay for rapid detection of toxigenic Vibrio cholerae O1 and O139.
TLDR
All the 38 stool samples positive for either O1 or O139 serogroup by PCR assay were also positive for the ctxA amplicon indicating that the O1 and O139 V. cholerae strains have the genetic potential of producing cholera toxin.
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Distinctiveness of Genotypes of Helicobacter pylori in Calcutta, India
ABSTRACT The genotypes of 78 strains of Helicobacter pylori from Calcutta, India (55 from ulcer patients and 23 from more-benign infections), were studied, with a focus on putative virulence genes…
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