DEFB103A gene

Known as: beta defensin-3, DEFB-3, DEFENSIN, BETA, 3, FORMERLY 
This gene is involved in the microbicidal and cytotoxic activity of neutrophils.
National Institutes of Health

Papers overview

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Review
2013
Review
2013
The human genome contains a significant amount of sequence variation, from single nucleotide polymorphisms to large stretches of… (More)
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2010
2010
Beta-defensins are antimicrobial peptides with an essential role in the innate immune response. In addition beta-defensins can… (More)
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Highly Cited
2009
Highly Cited
2009
The commensal fungus Candida albicans causes oropharyngeal candidiasis (OPC; thrush) in settings of immunodeficiency. Although… (More)
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Highly Cited
2007
Highly Cited
2007
To survive during colonization or infection of the human body, microorganisms must circumvent mechanisms of innate host defense… (More)
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Highly Cited
2006
Highly Cited
2006
Previously, we showed that human epithelial cell-derived beta-defensins (hBD)-2 and -3 block HIV-1 replication via a direct… (More)
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Highly Cited
2005
Highly Cited
2005
To investigate defensin gene copy number polymorphisms, a quantitative real-time PCR assay was developed and used to study DNA… (More)
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Highly Cited
2003
Highly Cited
2003
Human defensins form a family of small, cationic, and Cys-rich antimicrobial proteins that play important roles in innate… (More)
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Highly Cited
2003
Highly Cited
2003
Using a combination of multiplex amplifiable probe hybridization and semiquantitative fluorescence in situ hybridization (SQ-FISH… (More)
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Highly Cited
2001
Highly Cited
2001
Previous studies have shown the implication of beta-defensins in host defense of the human body. The human beta-defensins 1 and 2… (More)
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Highly Cited
1999
Highly Cited
1999
One component of host defense at mucosal surfaces is epithelium-derived peptides with antimicrobial activity called defensins. We… (More)
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