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DEFB103A gene
Known as:
beta defensin-3
, DEFB-3
, DEFENSIN, BETA, 3, FORMERLY
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This gene is involved in the microbicidal and cytotoxic activity of neutrophils.
National Institutes of Health
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Related topics
Related topics
9 relations
Antimicrobial Effect
Beta-Defensin 103
DEFB1 gene
DEFB103B gene
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DEFB103A wt Allele
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis
H. Conti
,
F. Shen
,
+11 authors
S. Gaffen
Journal of Experimental Medicine
2009
Corpus ID: 1410702
The commensal fungus Candida albicans causes oropharyngeal candidiasis (OPC; thrush) in settings of immunodeficiency. Although…
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Highly Cited
2008
Highly Cited
2008
Evaluation of the inhibitory effects of human serum components on bactericidal activity of human beta defensin 3
G. Maisetta
,
M. Luca
,
+5 authors
G. Batoni
Peptides
2008
Corpus ID: 25509837
Highly Cited
2007
Highly Cited
2007
Gram-positive three-component antimicrobial peptide-sensing system
Min Li
,
Y. Lai
,
A. Villaruz
,
David J. Cha
,
D. Sturdevant
,
M. Otto
Proceedings of the National Academy of Sciences
2007
Corpus ID: 1603817
To survive during colonization or infection of the human body, microorganisms must circumvent mechanisms of innate host defense…
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Highly Cited
2007
Highly Cited
2007
Susceptibility of various oral bacteria to antimicrobial peptides and to phagocytosis by neutrophils.
S. Ji
,
J. Hyun
,
E. Park
,
B-L Lee
,
K-K Kim
,
Y. Choi
Journal of Periodontal Research
2007
Corpus ID: 12609325
BACKGROUND AND OBJECTIVE The aim of this study was to compare the susceptibility of nonperiodontopathic and periodontopathic…
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Highly Cited
2006
Highly Cited
2006
In Vitro Bactericidal Activity of Human β-Defensin 3 against Multidrug-Resistant Nosocomial Strains
G. Maisetta
,
G. Batoni
,
+4 authors
M. Campa
Antimicrobial Agents and Chemotherapy
2006
Corpus ID: 12289595
ABSTRACT The antimicrobial activity of human β-defensin 3 (hBD-3) against multidrug-resistant clinical isolates of Staphylococcus…
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Highly Cited
2003
Highly Cited
2003
Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human β-defensin 3
Zhibin Wu
,
D. Hoover
,
+5 authors
Wuyuan Lu
Proceedings of the National Academy of Sciences…
2003
Corpus ID: 20105839
Human defensins form a family of small, cationic, and Cys-rich antimicrobial proteins that play important roles in innate…
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Highly Cited
2003
Highly Cited
2003
Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster.
E. Hollox
,
J. Armour
,
J. Barber
American Journal of Human Genetics
2003
Corpus ID: 25778430
Using a combination of multiplex amplifiable probe hybridization and semiquantitative fluorescence in situ hybridization (SQ-FISH…
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Highly Cited
2001
Highly Cited
2001
Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of…
Jolai R. Garcia
,
F. Jaumann
,
+10 authors
R. Bals
Cell and Tissue Research
2001
Corpus ID: 31033847
Previous studies have shown the implication of beta-defensins in host defense of the human body. The human beta-defensins 1 and 2…
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Review
2001
Review
2001
Discovery of new human beta-defensins using a genomics-based approach.
H. Jia
,
B. Schutte
,
+8 authors
P. McCray
Gene
2001
Corpus ID: 13702761
Epithelial beta-defensins are broad-spectrum cationic antimicrobial peptides that also act as chemokines for adaptive immune…
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Highly Cited
1999
Highly Cited
1999
Mouse β-Defensin 3 Is an Inducible Antimicrobial Peptide Expressed in the Epithelia of Multiple Organs
R. Bals
,
Xiaorong Wang
,
+4 authors
James M. Wilson
Infection and Immunity
1999
Corpus ID: 23256653
ABSTRACT One component of host defense at mucosal surfaces is epithelium-derived peptides with antimicrobial activity called…
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