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Calprotectin (MRP8/14 protein complex) release during mycobacterial infection in vitro and in vivo.
The calprotectin (MRP8/14) protein complex belongs to the S100 family of Ca2+ binding proteins and is expressed during myelomonocytic differentiation. MRP8/14 plasma levels were determined by ELISAExpand
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Differential action of cycloheximide and activation stimuli on transcription of tumor necrosis factor-alpha, IL-1 beta, IL-8, and P53 genes in human monocytes.
In the present study we have analyzed superinduction of TNF-alpha mRNA and enhancement of TNF-alpha gene transcription by cycloheximide (Chx) in human blood monocytes isolated by continuous PercollExpand
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Induction of tumor necrosis factor synthesis in human monocytes treated by transcriptional inhibitors.
Human blood monocytes and lymphocytes were separated by Percoll gradient fractionation. The synthesis of RNA was inhibited by actinomycin D (AcD) or alpha-amanitin (Amn). Monocytes were stimulatedExpand
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The difference in p53 antioncogene transcription in human monocytes and lymphocytes.
The p53 gene is associated with malignant transformation as well as 'antioncogene' activity. In this report expression of p53 in resting and activated human blood monocytes and lymphocytes wasExpand
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Enzyme-linked immunosorbent assay for human MRP-8/MRP-14 proteins and their quantitation in plasma of hematological patients.
We developed a quantitative enzyme immunoassay for human MRP-8/MRP-14, neutrophil cytosolic proteins with calcium-binding and bacteriastatic properties. MRP-8/MRP-14 concentrations were measured inExpand
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Tumor necrosis factor α induction in human monocytes
Abstract The present study was undertaken to assess the presence of tumor necrosis factor (TNF)-α mRNA and protein in circulating human blood monocytes and to study the TNF-α gene expression in humanExpand
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[Effects of human defensin HNP-1 on the production of tumor necrosis factor-alpha by human blood monocytes in vitro].
The influence of human defensin HNP-1 on the synthesis of tumor necrosis factor-alpha (TNF-alpha) by human blood monocytes was studied. It was shown that TNF-alpha production by human monocytesExpand
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Tumor necrosis factor alpha induction in human monocytes.
The present study was undertaken to assess the presence of tumor necrosis factor (TNF)-alpha mRNA and protein in circulating human blood monocytes and to study the TNF-alpha gene expression in humanExpand
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Effect of defensin HNP-1 of human neutrophils on production of tumor necrosis factor α by human blood monocytes in vitro
7. 8. 9. 10. 11. 12. 13. 14. 15. R. B. Holtzman, J. Zemaitis, L. Adler, et al., Prostaglandins, 37, No. 4, 481 (1989). R. M. Jones, M. R. Prasad, and D. K. Das, Molec. Cell. Biochem., 98, 161 (1990).Expand
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