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DU 6859A

Known as: DU-6859A 
National Institutes of Health

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2 relations

Broader (2)

Spiro Compoundssitafloxacin

Papers overview

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1998
1998
Therapeutic effects of a new quinolone, DU-6859a, on polymicrobial infections in a newly designed model of rat uterine endometritis.
We evaluated the efficacy of a new quinolone, DU-6859a, using a new model of rat uterine endometritis. Rats were infected with… 
Review
1998
Review
1998
[Chemotherapeutic agents under study].
The development of new drugs with strong antituberculous activity and fewer side effects which are not cross-resistant to… 
1997
1997
Antimicrobial activity of a new fluoroquinolone, DU-6859a, against quinolone-resistant clinical isolates of Neisseria gonorrhoeae with genetic alterations in the GyrA subunit of DNA gyrase and the…
The in-vitro antimicrobial activity of DU-6859a, a new fluoroquinolone, was tested against 55 clinical isolates of Neisseria… 
1997
1997
Comparative in vitro activities of DU-6859a, levofloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against 387 aerobic and anaerobic bite wound isolates
The activities of DU-6859a, levofloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against bite wound isolates were determined… 
Highly Cited
1996
Highly Cited
1996
MIC and time-kill study of activities of DU-6859a, ciprofloxacin, levofloxacin, sparfloxacin, cefotaxime, imipenem, and vancomycin against nine penicillin-susceptible and -resistant pneumococci
MIC and time-kill methods were used to test the activities of DU-6859a, ciprofloxacin, levofloxacin, sparfloxacin, cefotaxime… 
1996
1996
Effect of growth conditions on antimicrobial activity of DU-6859a and its bactericidal activity determined by the killing curve method.
The effect of growth conditions on the antibacterial activity of DU-6859a against Staphylococcus auerus, Escherichia coli, and… 
Highly Cited
1995
Highly Cited
1995
Contribution of the C-8 substituent of DU-6859a, a new potent fluoroquinolone, to its activity against DNA gyrase mutants of Pseudomonas aeruginosa
Inhibitory effects of five quinolones against DNA gyrases purified from four quinolone-resistant clinical isolates of Pseudomonas… 
1995
1995
Bactericidal activity of the new 4-quinolones DU-6859a and DV-7751a.
The bactericidal activity of two new 4-quinolones, DU-6859a and DV-7751a, was investigated against strains of Escherichia coli… 
1994
1994
Comparative in vitro activity of DU-6859a, a new fluoroquinolone agent, against gram-positive cocci
The in vitro activity of DU-6859a (DU), a new fluoroquinolone agent, was evaluated against 233 gram-positive cocci and was… 
1993
1993
In vitro activity of DU-6859a, a new fluorocyclopropyl quinolone
DU-6859a was tested against 844 recent clinical isolates (most from bacteremias) by using reference MIC determination procedures… 
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