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sitafloxacin

Known as: 3-Quinolinecarboxylic acid, 7-(7-amino-5-azaspiro(2.4)hept-5-yl)-8-chloro-6-fluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-, (1R-(1alpha(S*),2alpha))-, 7-(7-amino-5-azaspiro(2.4)heptan-5-yl)-8-chloro-6-fluoro-1-(2-fluorocyclopropyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid sesquihydrate, 7-[(7S)-7-Amino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Hydrate 
 
National Institutes of Health

Papers overview

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Review
2007
Review
2007
Pseudomonas aeruginosa is a major cause of nosocomial infections. This organism shows a remarkable capacity to resist antibiotics… Expand
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Highly Cited
2004
Highly Cited
2004
ABSTRACT Genome studies suggest that DNA gyrase is the sole type II topoisomerase and likely the unique target of quinolones in… Expand
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Highly Cited
2003
Highly Cited
2003
Staphylococcus aureus strain HMC3 isolated at the Hershey Medical Center, was resistant to vancomycin (VRSA) through the presence… Expand
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Highly Cited
2003
Highly Cited
2003
Background  Fluoroquinolone antibiotics (FQs) are associated with phototoxic skin reactions following exposure to sunlight. 
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Highly Cited
2001
Highly Cited
2001
ABSTRACT A total of 1,531 recent clinical isolates of Streptococcus pneumoniae were collected from 33 medical centers nationwide… Expand
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Review
2001
Review
2001
A number of new fluoroquinolone antibacterials have been released for clinical use in recent years. These new agents exhibit… Expand
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Review
2000
Review
2000
The history of the development of the quinolones is described from the first quinolone, nalidixic acid, via the first 6… Expand
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Highly Cited
2000
Highly Cited
2000
  • P. Ball
  • The Journal of antimicrobial chemotherapy
  • 2000
  • Corpus ID: 19018626
days 3‐5 of therapy have indicated a mean prolongation of QTc of 6 ms (� 26 ms) in 9.5% of moxifloxacin-treated patients compared… Expand
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Highly Cited
2000
Highly Cited
2000
ABSTRACT The in vitro activities of sitafloxacin, ciprofloxacin, trovafloxacin, levofloxacin, clinafloxacin, gatifloxacin, and… Expand
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1996
1996
In extracts of human platelets, three isoenzymes of cyclic nucleotide phosphodiesterase (PDE), namely, PDE2, PDE3, and PDE5, were… Expand
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