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DNA topoisomerase type II activity

Known as: topoisomerase II, type II DNA topoisomerase activity, DNA topoisomerase IV activity 
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second… 
National Institutes of Health

Related topics

Related topics

4 relations
DNA Topoisomerase IVDNA topoisomerase II alphaTopoisomerase II

Broader (1)

topoisomerase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Phylogenetic analysis of the core histone doublet and DNA topo II genes of Marseilleviridae: evidence of proto-eukaryotic provenance
While the genomes of eukaryotes and Archaea both encode the histone-fold domain, only eukaryotes encode the core histone paralogs… 
2015
2015
ATPS-68COMBINATION OF TOPOISOMERASE II POISON BERUBICIN WITH STAT3 INHIBITOR WP1066BLOCKS POTENTLY TUMOR GROWTH IN GMB MODELS
BACKGROUND: Berubicin (WP744) is a DNA binding agent and potent topoisomerase II poison designed and synthesized in our… 
Review
2015
Review
2015
IS METABOLIC ACTIVATION OF TOPOISOMERASE II POISONS IMPORTANT IN THE MECHANISM OF CYTOTOXICITY?
The antitumor drugs doxorubicin and etoposide, a phodophyllotoxin derivative, are clinically active for the treatment of human… 
2015
2015
Eukaryotic core histone diversification in light of the histone doublet and DNA topo II genes of Marseilleviridae
While eukaryotic and archaean genomes encode the histone fold domain, only eukaryotes encode the core histones H2A, H2B, H3, and… 
2002
2002
Redox control of cell cycle-coupled topoisomerase II alpha gene expression.
1994
1994
THE ANTICANCER EFFECT AND ANTI－DNA TOPOISOMERASE II EFFECT OF EXTRACTS OF CAMELLIA PTILOPHYLLA CHANG AND CAMELLIA SINENSIS
ＴＨＥＡＮＴＩＣＡＮＣＥＲＥＦＦＥＣＴＡＮＤＡＮＴＩ－ＤＮＡＴＯＰＯＩＳＯＭＥＲＡＳＥＩＩＥＦＦＥＣＴＯＦＥＸＴＲＡＣＴＳＯＦＣＡＭＥＬＬＩＡＰＴＩＬＯＰＨＹＬＬＡＣＨＡＮＧＡＮＤＣＡＭＥＬＬＩＡＳＩＮＥＮＳＩＳＸｉｅＢｉｎｓｆｅｎ；谢冰芬；ＬｉｕＺ... 
1993
1993
[The cytotoxicity and action mechanism of ranunculin in vitro].
This paper describes the cytotoxicity of ranunculin (RAN) and its mechanism of action. The IC50 of RAN against the KB and Bel7402… 
1993
1993
Analysis of topoisomerase II‐mediated DNA cleavage of the c‐myc gene during HL60 differentiation
Highly Cited
1988
Highly Cited
1988
Differential expression of DNA topoisomerases I and II during the eukaryotic cell cycle.
We have utilized antibody probes to examine the expression of DNA topoisomerases I and II and chromosome scaffold protein Sc-2 in… 
Highly Cited
1988
Highly Cited
1988
Proliferation-dependent regulation of DNA topoisomerase II in cultured human cells.
The intracellular level of DNA topoisomerase II appears to be reversibly regulated by serum concentration in cultured primary… 
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