DNA topoisomerase type II activity

Known as: topoisomerase II, type II DNA topoisomerase activity, DNA topoisomerase IV activity 
Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second… (More)
National Institutes of Health

Papers overview

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1999
1999
We have dissected the topoisomerase II gene of members of the two recently characterized subgroups of Trypanosoma cruzi to obtain… (More)
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1995
1995
Domain-specific anti-Drosophila DNA topoisomerase II antibodies were generated, affinity purified and used for confocal laser… (More)
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1993
1993
Stabilization of crossings of pairs of DNA helices by binding of eukaryotic DNA topoisomerase II was studied by two types of… (More)
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1993
1993
The maxicircle of the parasitic protozoan Trypanosoma brucei, one component of the mitochondrial genome, has size differences… (More)
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1993
1993
This paper describes the cytotoxicity of ranunculin (RAN) and its mechanism of action. The IC50 of RAN against the KB and Bel7402… (More)
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1993
1993
We have investigated the effect of mAMSA, a potent topoisomerase II inhibitor, on the c-myc proto-oncogene of the acute… (More)
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1992
1992
Ninety quinolones were evaluated to determine whether their ability to induce mammalian topoisomerase II mediated DNA cleavage in… (More)
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Highly Cited
1988
Highly Cited
1988
We have utilized antibody probes to examine the expression of DNA topoisomerases I and II and chromosome scaffold protein Sc-2 in… (More)
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Highly Cited
1988
Highly Cited
1988
The intracellular level of DNA topoisomerase II appears to be reversibly regulated by serum concentration in cultured primary… (More)
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