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DEPTOR gene

Known as: DEP.6, FLJ12428, DEP DOMAIN-CONTAINING PROTEIN 6 
This gene plays a role in mTOR-mediated signaling.
National Institutes of Health

Related topics

Related topics

5 relations
ApoptosisDEP Domain-Containing mTOR-Interacting ProteinSignal TransductionSignal Transduction Inhibition

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Amino Acid- and Insulin-Induced Activation of mTORC1 in Neonatal Piglet Skeletal Muscle Involves Sestin2-GATOR2, Rag A/C-mTOR, and RHEB-mTOR Complex Formation.
Background Feeding stimulates protein synthesis in skeletal muscle of neonates and this response is regulated through activation… 
2017
2017
Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer
Argininosuccinate synthetase 1 (ASS1) is a rate-limiting enzyme in arginine biosynthesis. Although ASS1 expression levels are… 
2017
2017
Different functions of DEPTOR in modulating sensitivity to chemotherapy for esophageal squamous cell carcinoma
2016
2016
Inhibition of neddylation regulates dendritic cell functions via Deptor accumulation driven mTOR inactivation
Neddylation, a newly identified post-translational modification, is significant for the activity and stability of target proteins… 
2016
2016
Cul1 promotes melanoma cell proliferation by promoting DEPTOR degradation and enhancing cap-dependent translation.
Cullin1 (Cul1) serves as a rigid scaffold in the SCF (Skp1/Cullin/Rbx1/F-box protein) E3 ubiquitin ligase complex and has been… 
2016
2016
DEPTOR in POMC neurons affects liver metabolism but is dispensable for the regulation of energy balance.
We have recently demonstrated that specific overexpression of DEP-domain containing mTOR-interacting protein (DEPTOR) in the… 
2015
2015
The Endosomal Sorting Complex Required for Transport Pathway Mediates Chemokine Receptor CXCR4-promoted Lysosomal Degradation of the Mammalian Target of Rapamycin Antagonist DEPTOR*
Background: Akt signaling is activated by G protein-coupled receptors (GPCRs) via the PI3K-mTORC2 signaling cascade, but… 
2010
2010
Structural Analysis and Functional Implications of the Negative mTORC 1 Regulator REDD 1 † , ‡
REDD1 is a conserved stress-response protein that regulates mTORC1, a critical regulator of cell growth and proliferation that is… 
2002
2002
Effect of Diesel Exhaust Particle Extracts on Collagen-induced Arthritis in Mice
We investigated the effect of diesel exhaust particles (DEP) extracts on collagen-induced arthritis (CIA) in mice. For this study… 
1991
1991
An analysis of the biochemical and biosynthetic properties of dentin phosphoprotein.
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