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DEPTOR gene
Known as:
DEP.6
, FLJ12428
, DEP DOMAIN-CONTAINING PROTEIN 6
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This gene plays a role in mTOR-mediated signaling.
National Institutes of Health
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Related topics
Related topics
5 relations
Apoptosis
DEP Domain-Containing mTOR-Interacting Protein
Signal Transduction
Signal Transduction Inhibition
Broader (1)
Genes
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
DEPTOR Suppresses Lipogenesis and Ameliorates Hepatic Steatosis and Acute-on-Chronic Liver Injury in Alcoholic Liver Disease Short Title — Defective Signaling of SIRT 1 and DEPTOR Contributes to…
Hanqing Chen
,
F. Shen
,
+18 authors
Mengwei Zang
2018
Corpus ID: 207865814
Department of Molecular Medicine, Barshop Institute for Longevity and Aging Studies, Center for Healthy Aging, University of…
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2017
2017
Structure-activity relationship study of small molecule inhibitors of the DEPTOR-mTOR interaction.
Jihye Lee
,
Yijiang Shi
,
+4 authors
A. Lichtenstein
Bioorganic & Medicinal Chemistry Letters
2017
Corpus ID: 5002118
2017
2017
DEPTOR promoter genetic variants and insulin resistance in obese children and adolescents
J. Kovač
,
Tamara Šutuš Temovski
,
+5 authors
P. Kotnik
Pediatric Diabetes
2017
Corpus ID: 9295341
Insulin resistance (IR) is one of the major metabolic complications of obesity in children and adolescents. DEP domain‐containing…
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2016
2016
DEPTOR in POMC neurons affects liver metabolism but is dispensable for the regulation of energy balance.
Alexandre Caron
,
Sébastien M. Labbé
,
+4 authors
M. Laplante
American Journal of Physiology. Regulatory…
2016
Corpus ID: 11634916
We have recently demonstrated that specific overexpression of DEP-domain containing mTOR-interacting protein (DEPTOR) in the…
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2015
2015
Androgen receptor functions as a negative transcriptional regulator of DEPTOR, mTOR inhibitor.
Yuichiro Kanno
,
Shuai Zhao
,
Naoya Yamashita
,
K. Yanai
,
K. Nemoto
,
Y. Inouye
Journal of Toxicological Sciences
2015
Corpus ID: 11168341
It has been noticed that crosstalk between androgen receptor (AR) and mammalian target of rapamycin (mTOR) signaling pathways…
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2015
2015
mTORC1 regulates cytokinesis through activation of Rho-ROCK signaling
Timothy R. Peterson
,
M. Laplante
,
Edo van Veen
,
M. V. Vugt
,
Carson C. Thoreen
,
D. Sabatini
2015
Corpus ID: 22766666
Understanding the mechanisms by which cells coordinate their size with their ability to divide has long attracted the interest of…
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2012
2012
Molecular mechanisms underlying the time-dependent autophagy and apoptosis induced by nutrient depletion in multiple myeloma: a pilot study
Yuan-Fei Liu
,
Yan Chen
,
Lu Wen
,
G. Cui
Journal of Huazhong University of Science and…
2012
Corpus ID: 195679461
SummaryThis study explored the molecular mechanisms underlying the time-dependent autophagy and apoptosis induced by nutrient…
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2010
2010
Structural Analysis and Functional Implications of the Negative mTORC 1 Regulator REDD 1 † , ‡
S. Vega-Rubín-de-Celis
,
Z. Abdallah
,
L. Kinch
,
N. Grishin
,
J. Brugarolas
,
Xuewu Zhang
2010
Corpus ID: 43855815
REDD1 is a conserved stress-response protein that regulates mTORC1, a critical regulator of cell growth and proliferation that is…
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1997
1997
Isospin dependent multifragmentation in 112Sn+ 112Sn and 124Sn+ 124Sn collisions
G. Kortemeyer
,
W. Bauer
,
G. Kunde
1997
Corpus ID: 6874087
Significant differences in the relationships between fragment, neutron, and charged particle multiplicities were found between…
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1991
1991
An analysis of the biochemical and biosynthetic properties of dentin phosphoprotein.
K. Ibaraki
,
H. Shimokawa
,
S. Sasaki
Matrix
1991
Corpus ID: 23180387
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