Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 235,430,679 papers from all fields of science
Search
Sign In
Create Free Account
DCK gene
Known as:
DCK
, DEOXYCYTIDINE KINASE
, Deoxycytidine Kinase Gene
This gene is involved in deoxyribonucleoside phosphorylation.
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
5 relations
Deoxycytidine Kinase
Drug Efflux
Drug resistance
Leukemia, Myelocytic, Acute
Expand
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Nonenantioselectivity property of human deoxycytidine kinase explained by structures of the enzyme in complex with L- and D-nucleosides.
E. Sabini
,
Saugata Hazra
,
M. Konrad
,
A. Lavie
Journal of Medicinal Chemistry
2007
Corpus ID: 22299249
Biological molecules are predominantly enantioselective. Yet currently two nucleoside analogue prodrugs (3TC and FTC) with…
Expand
1986
1986
Arabinosyl-5-azacytosine: mechanisms of native and acquired resistance.
G. Ahluwalia
,
M. Cohen
,
+7 authors
D. Johns
Cancer Research
1986
Corpus ID: 26710545
Factors influencing the activity of the nucleoside analogue arabinosyl-5-azacytosine (ara-AC) were studied in P388 murine…
Expand
1985
1985
Improved synthesis of 2'-deoxyformycin A and studies of its in vitro activity against mouse lymphoma of T-cell origin.
A. Rosowsky
,
V. Solan
,
L. Gudas
Journal of Medicinal Chemistry
1985
Corpus ID: 24351071
7-Amino-3-(2'-deoxy-beta-D-ribofuranosyl)pyrazolo[4,3-d]pyrimidine (2'-deoxyformycin A) was synthesized from formycin A by a…
Expand
1985
1985
Pyrimidine salvage enzymes in human tonsil lymphocytes: II. Purification and properties of deoxycytidine kinase.
K. Szyfter
,
M. Sasvári-Székely
,
T. Spasokukotskaja
,
F. Antoni
,
M. Staub
Acta biochimica et biophysica; Academiae…
1985
Corpus ID: 31298201
Human tonsillar lymphocytes incorporate about 7-10 times more [3H]-deoxy-thymidine than [3H]-deoxycytidine at the same…
Expand
1984
1984
S-adenosylhomocysteine hydrolase inactivation and purine toxicity in cultured human T- and B-lymphoblasts.
G. J. Young
,
L. Hallam
,
I. Jack
,
M. van der Weyden
Journal of Laboratory and Clinical Medicine
1984
Corpus ID: 44398150
Accumulation of intracellular deoxyadenosine triphosphate and inactivation of the enzyme S-adenosylhomocysteine hydrolase by…
Expand
Highly Cited
1981
Highly Cited
1981
Identification of the mechanism of activation of 9-beta-D-arabinofuranosyladenine in human lymphoid cells using mutants deficient in nucleoside kinases.
V. Verhoef
,
J. Sarup
,
A. Fridland
Cancer Research
1981
Corpus ID: 25611729
The biochemical basis of cellular resistance to 9-beta-D-arabinofuranosyladenine (ara-A) and its natural purine derivative…
Expand
1980
1980
Purine ribonucleoside and deoxyribonucleoside kinase activities in thymocytes. Specificity and optimal assay conditions for phosphorylation.
T. Lukey
,
F. Snyder
Canadian Journal of Biochemistry
1980
Corpus ID: 20573477
The optimal assay conditions and specificity for the principal reactions of purine nucleoside phosphorylation were studied in…
Expand
1979
1979
Abnormal metabolism of thymidine nucleotides and phosphorylation of deoxycytidine in Escherichia coli C thy- ura- mutant.
T. Ohkawa
European Journal of Biochemistry
1979
Corpus ID: 1034607
The Escherichia coli C thy−ura− mutant (Thy A-35) shows a rate of DNA replication (or chain elongation) one-half that of the…
Expand
1977
1977
Cell-free synthesis of herpes simplex virus-coded pyrimidine deoxyribonucleoside kinase enzyme
C. Preston
Journal of Virology
1977
Corpus ID: 9808633
The incubation of a cell-free protein-synthesizing system prepared from rabbit reticulocytes with cytoplasmic RNA from herpes…
Expand
1977
1977
Irreversible enzyme inhibitors. 200. Active-site-directed inhibitors of deoxycytidine kinase.
A. Ward
,
B. R. Baker
Journal of Medicinal Chemistry
1977
Corpus ID: 22172911
Forty-three pyrimidine derivatives, mainly containing the 4-aminopyrimidine system, have been prepared and evaluated as…
Expand