Skip to search formSkip to main contentSkip to account menu

Cytochrome P-450 CYP2E1

Known as: Cytochrome P 450 IIE1, N Nitrosodimethylamine Demethylase, CYP2E1 
An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
Highly Cited
2001
Highly Cited
2001
Earlier studies have shown highly exaggerated mechanism-based liver injury of thioacetamide (TA) in rats following moderate diet… 
Highly Cited
2000
Highly Cited
2000
Differences in biotransformation activities may alter the bioavailability or efficacy of drugs, provide protection from certain… 
Highly Cited
1995
Highly Cited
1995
Msp I polymorphism and exon 7 Ile-Val polymorphism of CYP1A1, and Rsa I polymorphism of CYP2E1 were studied in lung cancer… 
Highly Cited
1994
Highly Cited
1994
Polymorphic metabolism of certain chemical carcinogens may result in differences in susceptibility to cancers. Human CYP2E1…