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CYP2C18 protein, human

Known as: Cytochrome P450 2C18, Cytochrome P450, Subfamily IIC (Mephenytoin 4-Hydroxylase), Polypeptide 17, P450-2C18 
Cytochrome P450 2C18 (490 aa, ~56 kDa) is encoded by the human CYP2C18 gene. This protein plays a role in the electron transport chain.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
CYP2C19 is an important enzyme for human drug metabolism, and it also participates in the metabolism of endogenous substrates… Expand
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2006
2006
Background  Individuality in the expression and regulation of hepatic drug‐metabolizing enzymes (DMEs) and cytoprotective (CP… Expand
2002
2002
AIM The human cytochrome P-450 2C18(CYP2C18) has been characterized. However, the protein has not been purified from liver and… Expand
Highly Cited
2001
Highly Cited
2001
The expression and inducibility of four CYP2C genes, including CYP2C8, -2C9, -2C18, and -2C19, was investigated in primary… Expand
Review
2000
Review
2000
  • D. Eaton
  • Neurotoxicology
  • 2000
  • Corpus ID: 31590384
Numerous specific genetic polymorphisms (PM) in the multi-gene families of cytochromes P450 (CYPs) and glutathione S-transferases… Expand
1999
1999
It is well established that the variable binding‐site architecture and composition of the P450 metabolizing heme proteins are… Expand
Highly Cited
1999
Highly Cited
1999
The aim of this study was to re-examine the human hepatic metabolism of diclofenac, with special focus on the generation of minor… Expand
1999
1999
Reverse transcription-PCR analysis in human epidermis, using primers from CYP2C18 and CYP2C19, revealed products containing… Expand
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Highly Cited
1998
Highly Cited
1998
1,1,1-Trichloro-2,2-bis(4-methoxyphenyl)ethane (methoxychlor) is a widely used pesticide that is pro-estrogenic. We have… Expand
1991
1991
Sequencing of genomic polymerase chain reaction (PCR) products synthesized using primers generated from the CYP2C8 and CYP2C9… Expand