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4-nitrophenol 2-monooxygenase activity
Known as:
4-nitrophenol hydroxylase activity
, 4-nitrophenol,NADH:oxygen oxidoreductase (2-hydroxylating)
, 4-nitrophenol-2-hydroxylase activity
Catalysis of the reaction: 4-nitrophenol + H(+) + NADH + O(2) = 4-nitrocatechol + H(2)O + NAD(+). [EC:1.14.13.29, RHEA:12571]
National Institutes of Health
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Related topics
Related topics
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Cytochrome P-450 CYP2E1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2003
2003
Heterologous expression of human cytochrome P450 2E1 in HepG2 cell line.
J. Zhuge
,
Y. Luo
,
Ying-nian Yu
World journal of gastroenterology
2003
Corpus ID: 46060458
AIM Human cytochrome P-450 2E1 (CYP2E1) takes part in the biotransformation of ethanol, acetone, many small-molecule substrates…
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2003
2003
Modulation of rat liver cytochrome P450 by protein restriction assessed by biochemical and bacterial mutagenicity methods [corrected].
L. Cancino-Badías
,
R. Reyes
,
+7 authors
J. Espinosa-Aguirre
Mutagenesis
2003
Corpus ID: 22733131
Protein restriction (PR) significantly inhibits spontaneous and chemical carcinogenesis. Several factors seem to be involved in…
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Highly Cited
2002
Highly Cited
2002
In vivo and in vitro induction of cytochrome P450 enzymes in beagle dogs.
R. Graham
,
April Downey
,
+5 authors
A. Parkinson
Drug metabolism and disposition: the biological…
2002
Corpus ID: 11703351
The aim of this study was to determine the in vitro and in vivo effects of several prototypical inducers, namely beta…
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Highly Cited
1997
Highly Cited
1997
Inhibition of cytochrome P450 2E1 expression by 2-(allylthio)pyrazine, a potential chemoprotective agent: hepatoprotective effects.
N. Kim
,
M. K. Kwak
,
S. Kim
Biochemical pharmacology
1997
Corpus ID: 22976949
Cytochrome P450 2E1 (P450 2E1) is active in both the detoxification and activation of small organic molecules. The effects of 2…
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Highly Cited
1997
Highly Cited
1997
Both cytochromes P450 2E1 and 3A are involved in the O-hydroxylation of p-nitrophenol, a catalytic activity known to be specific for P450 2E1.
A. Zérilli
,
D. Ratanasavanh
,
+5 authors
F. Berthou
Chemical research in toxicology
1997
Corpus ID: 37122939
4-Nitrophenol 2-hydroxylation activity was previously shown to be mainly catalyzed by P450 2E1 in animal species and humans. As…
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1997
1997
Selective inhibition and induction of CYP activity discriminates between the isoforms responsible for the activation of butylated hydroxytoluene and naphthalene in mouse lung.
R. Verschoyle
,
J. Martin
,
D. Dinsdale
Xenobiotica; the fate of foreign compounds in…
1997
Corpus ID: 25469738
1. Selective induction and inhibition experiments have been used to identify the cytochrome P450 (CYP) isoforms responsible for…
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Review
1993
Review
1993
Effects of caloric restriction on rodent drug and carcinogen metabolizing enzymes: implications for mutagenesis and cancer.
M. Manjgaladze
,
S. Chen
,
+5 authors
J. Leakey
Mutation research
1993
Corpus ID: 2208424
Caloric restriction in rodents results in increased longevity and a decreased rate of spontaneous and chemically induced…
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1993
1993
Acetone-dependent regulation of cytochromes P4502E1 and P4502B1 in rat nasal mucosa.
V. Longo
,
M. Ingelman-Sundberg
Biochemical pharmacology
1993
Corpus ID: 2465780
The inducibility and molecular regulation of cytochrome P4502E1 (CYP2E1) has been examined in nasal mucosa of rats after acetone…
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