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Cyclooxygenase 2 Inhibitors

Known as: Cyclooxygenase-2 Inhibitors, Inhibitors, COX2, COX2 Inhibitors 
A nonsteroidal anti-inflammatory drug used to relieve pain and inflammation. COX-2 inhibitors are being studied in the prevention of colon polyps… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Cyclooxygenase-2 isozyme is a promising anti-inflammatory drug target, and overexpression of this enzyme is also associated with… Expand
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Review
2001
Review
2001
Nonsteroidal antiinflammatory drugs (NSAIDs) are widely used to treat arthritis, menstrual pain, and headache. Although they are… Expand
Review
2001
Review
2001
Population-based studies have established that long-term intake of non-steroidal anti-inflammatory drugs (NSAIDs), compounds that… Expand
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Review
2000
Review
2000
BACKGROUND Patients with familial adenomatous polyposis have a nearly 100 percent risk of colorectal cancer. In this disease, the… Expand
Highly Cited
2000
Highly Cited
2000
We provide evidence that cyclooxygenase (COX)-2-derived prostaglandins contribute to tumor growth by inducing newly formed blood… Expand
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Review
1998
Review
1998
Cyclooxygenase (COX), first purified in 1976 and cloned in 1988, is the key enzyme in the synthesis of prostaglandins (PGs) from… Expand
Highly Cited
1998
Highly Cited
1998
To explore the role of cyclooxygenase (COX) in endothelial cell migration and angiogenesis, we have used two in vitro model… Expand
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Highly Cited
1998
Highly Cited
1998
Epidemiological and laboratory studies suggest that nonsteroidal antiinflammatory drugs reduce the risk of colon cancer and that… Expand
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Highly Cited
1997
Highly Cited
1997
A series of sulfonamide-containing 1,5-diarylpyrazole derivatives were prepared and evaluated for their ability to block… Expand
Highly Cited
1996
Highly Cited
1996
Two cyclooxygenase isozymes catalyze conversion of arachidonic acid to prostaglandin H2: constitutive COX-1 and inducible COX-2… Expand
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