Cyclooxygenase 2 Inhibitors

Known as: Cyclooxygenase-2 Inhibitors, Inhibitors, COX2, COX2 Inhibitors 
A nonsteroidal anti-inflammatory drug used to relieve pain and inflammation. COX-2 inhibitors are being studied in the prevention of colon polyps… (More)

Topic mentions per year

Topic mentions per year

1991-2018
020040019912018

Papers overview

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Highly Cited
2004
Highly Cited
2004
BACKGROUND Although cyclooxygenase-2 inhibitors (coxibs) were developed to cause less gastrointestinal hemorrhage than… (More)
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Highly Cited
2000
Highly Cited
2000
We provide evidence that cyclooxygenase (COX)-2-derived prostaglandins contribute to tumor growth by inducing newly formed blood… (More)
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Highly Cited
2000
Highly Cited
2000
Cyclooxygenase-2 (COX-2; Ptgs2) acts as a tumor promoter in rodent models for colorectal cancer, but its precise role in… (More)
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Highly Cited
2000
Highly Cited
2000
This study investigates the apoptotic activity of the cyclooxygenase-2 (COX-2) inhibitor celecoxib in prostate carcinoma cells… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND & AIMS Selective cyclooxygenase (COX)-2 inhibitors produce less gastric damage than conventional nonsteroidal anti… (More)
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Highly Cited
1998
Highly Cited
1998
To explore the role of cyclooxygenase (COX) in endothelial cell migration and angiogenesis, we have used two in vitro model… (More)
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Highly Cited
1998
Highly Cited
1998
Epidemiological and laboratory studies suggest that nonsteroidal antiinflammatory drugs reduce the risk of colon cancer and that… (More)
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Highly Cited
1996
Highly Cited
1996
Two cyclooxygenase isozymes catalyze conversion of arachidonic acid to prostaglandin H2: constitutive COX-1 and inducible COX-2… (More)
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Highly Cited
1996
Highly Cited
1996
Epidemiological and laboratory studies indicate an inverse relationship between the risk of colon cancer development and intake… (More)
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Highly Cited
1994
Highly Cited
1994
We have examined the role of cyclooxygenase 2 (COX-2) in a model of inflammation in vivo. Carrageenan administration to the… (More)
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