Skip to search formSkip to main contentSkip to account menu

Cyclooxygenase 2 Inhibitors

Known as: Cyclooxygenase-2 Inhibitors, Inhibitors, COX2, COX2 Inhibitors 
A nonsteroidal anti-inflammatory drug used to relieve pain and inflammation. COX-2 inhibitors are being studied in the prevention of colon polyps… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Cyclooxygenase-2 isozyme is a promising anti-inflammatory drug target, and overexpression of this enzyme is also associated with… 
Review
2001
Review
2001
Population-based studies have established that long-term intake of non-steroidal anti-inflammatory drugs (NSAIDs), compounds that… 
Review
2001
Review
2001
Nonsteroidal antiinflammatory drugs (NSAIDs) are widely used to treat arthritis, menstrual pain, and headache. Although they are… 
Review
2001
Review
2001
Atherosclerosis is a process with inflammatory features and selective cyclooxygenase 2 (COX-2) inhibitors may potentially have… 
Review
2000
Review
2000
BACKGROUND Patients with familial adenomatous polyposis have a nearly 100 percent risk of colorectal cancer. In this disease, the… 
Highly Cited
2000
Highly Cited
2000
We provide evidence that cyclooxygenase (COX)-2-derived prostaglandins contribute to tumor growth by inducing newly formed blood… 
Review
1998
Review
1998
Cyclooxygenase (COX), first purified in 1976 and cloned in 1988, is the key enzyme in the synthesis of prostaglandins (PGs) from… 
Highly Cited
1998
Highly Cited
1998
Epidemiological and laboratory studies suggest that nonsteroidal antiinflammatory drugs reduce the risk of colon cancer and that… 
Highly Cited
1997
Highly Cited
1997
A series of sulfonamide-containing 1,5-diarylpyrazole derivatives were prepared and evaluated for their ability to block… 
Highly Cited
1994
Highly Cited
1994
We have examined the role of cyclooxygenase 2 (COX-2) in a model of inflammation in vivo. Carrageenan administration to the…