celecoxib

Known as: 4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide, Celecoxib [Chemical/Ingredient], Célécoxib 
A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Objective To characterise the determinants, time course, and risks of acute myocardial infarction associated with use of oral non… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Observational studies and randomized trials have reported increased cardiovascular risk associated with cyclooxygenase… (More)
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Highly Cited
2006
Highly Cited
2006
Signs of an inflammatory process, in particular increased pro-inflammatory cytokines and increased levels of prostaglandine E2… (More)
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Highly Cited
2005
Highly Cited
2005
BACKGROUND & AIMS Data indicate that cyclooxygenase-2-specific inhibitors cause less gastroduodenal mucosal damage than… (More)
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Highly Cited
2002
Highly Cited
2002
Cyclooxygenase-2 (COX-2) is expressed within neovascular structures that support many human cancers. Inhibition of COX-2 by… (More)
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Highly Cited
2001
Highly Cited
2001
The regular use of various nonsteroidal anti-inflammatory drugs (NSAIDs) was shown to decrease the incidence of colorectal cancer… (More)
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Highly Cited
2000
Highly Cited
2000
CONTEXT Conventional nonsteroidal anti-inflammatory drugs (NSAIDs) are associated with a spectrum of toxic effects, notably… (More)
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Highly Cited
2000
Highly Cited
2000
Epidemiological observations and laboratory research have suggested that nonsteroidal anti-inflammatory drugs (NSAIDs) reduce the… (More)
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Highly Cited
1999
Highly Cited
1999
CONTEXT In vitro studies have shown that celecoxib inhibits cyclooxygenase 2 (COX-2) but not COX-1, suggesting that this drug may… (More)
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Highly Cited
1998
Highly Cited
1998
Epidemiological and laboratory studies suggest that nonsteroidal antiinflammatory drugs reduce the risk of colon cancer and that… (More)
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