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A Means to Address Regional Variability in Intestinal Drug Absorption
TLDR
The concept of the absorption window is reviewed and the performance evaluation of GRDDS is described, including in vitro-in vivo correlation studies and potential use.
Analytical techniques for quantification of amorphous/crystalline phases in pharmaceutical solids.
TLDR
The present review provides a compilation of the theoretical and practical aspects of existing techniques, thereby facilitating the selection of an appropriate technique to accomplish various objectives of quantification of amorphous systems.
Compression physics in the formulation development of tablets.
TLDR
Various properties of drugs and excipients, such as moisture content, particle size and distribution, polymorphism, amorphism, crystal habit, hydration state, and lubricant and binder level of the blend that have an influence on compaction are discussed.
Polymorphs, Salts, and Cocrystals: What’s in a Name?
The December 2011 release of a draft United States Food and Drug Administration (FDA) guidance concerning regulatory classification of pharmaceutical cocrystals of active pharmaceutical ingredients
Solid State Characterization of Commercial Crystalline and Amorphous Atorvastatin Calcium Samples
TLDR
Commercial ATC samples exhibited diverse solid state behavior that can impact the performance and stability of the dosage forms, according to the objective of this study.
ASC: an associative-computing paradigm
TLDR
A parallel programming paradigm called ASC (ASsociative Computing), designed for a wide range of computing engines, that incorporates data parallelism at the base level, so that programmers do not have to specify low-level sequential tasks such as sorting, looping and parallelization.
Role of molecular interaction in stability of celecoxib-PVP amorphous systems.
TLDR
A comprehensive characterization of CEL-PVP binary amorphous systems by thermal, spectroscopic, and computer simulation techniques provided greater insight into the molecular interaction between the two species.
Characterization of solid-state forms of celecoxib.
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