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Cucurbitacins

Known as: 19-Norlanosta-1,5-diene-3,11,22-trione, 16,24-epoxy-2,25-dihydroxy-9-methyl-, (9beta,10alpha,16alpha,24S)-, Cucurbitacins [Chemical/Ingredient], cucurbitacin 
Triterpenes that derive from LANOSTEROL by a shift of the C19 methyl to the C9 position. They are found in seeds and roots of CUCURBITACEAE and other… 
National Institutes of Health

Related topics

Related topics

13 relations

Narrower (4)

23,24-dihydrocucurbitacin Fcucurbitacin IIacucurbitacin IIbfevicordin-A
In BloodProcess of secretionagonistsantagonists & inhibitors

Broader (1)

Triterpenes

Papers overview

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2014
2014
Downregulation of endogenous STAT3 augments tumoricidal activity of interleukin 15 activated dendritic cell against lymphoma and leukemia via TRAIL.
2012
2012
Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest
Purpose. To explore the effects of cucurbitacin B on the radiation survival of human breast cancer cells and to elucidate the… 
2011
2011
Apoptosis induction through proteasome inhibitory activity of cucurbitacin D in human T‐cell leukemia
Human T‐cell leukemia is an aggressive malignancy of T lymphocytes. T‐cell leukemia has a very poor prognosis, even with… 
2008
2008
Development of a STAT3 reporter prostate cancer cell line for high throughput screening of STAT3 activators and inhibitors.
Highly Cited
2007
Highly Cited
2007
Bioactive saponins and glycosides. XXVII. Structures of new cucurbitane-type triterpene glycosides and antiallergic constituents from Citrullus colocynthis.
The methanolic extract from the fruit of Citrullus colocynthis showed an inhibitory effect on ear passive cutaneous anaphylaxis… 
2006
2006
Pregnane, coumarin and lupane derivatives and cytotoxic constituents from Helicteres angustifolia.
2003
2003
Cytotoxic cucurbitacin constituents from Sloanea zuliaensis.
A new cucurbitacin D analogue, 2-deoxycucurbitacin D (1), as well as cucurbitacin D (2) and 25-acetylcucurbitacin F (3) were… 
2000
2000
Inhibition of T-lymphocyte proliferation by cucurbitacins from Picrorhiza scrophulariaeflora.
Two cucurbitacin aglycons were isolated from the dried rhizomes of Picrorhiza scrophulariaeflora and were identified as 25… 
1998
1998
Complement-inhibiting cucurbitacin glycosides from Picria fel-terrae.
Four cucurbitacin glycosides were isolated from Picriafel-terrae and identified by MS and NMR spectroscopy as picfeltarraenin IA… 
1993
1993
Cucurbitacins as Constituents of Wilbrandia ebracteata.
The methanolic extract from the roots of WILBRANDIA EBRACTEATA afforded, in addition to the known dihydrocucurbitacins B and E… 
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