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Metabolic activation of natural phenols into selective oxidative burst agonists by activated human neutrophils.
Phenols isolated from the traditional medicinal plant Picrorhiza kurroa inhibit the release of superoxide anion (O2-) by activated human neutrophils, but leave the phagocytotic capacity intact.Expand
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Effects of methoxylation of apocynin and analogs on the inhibition of reactive oxygen species production by stimulated human neutrophils.
Owing to their multiple side effects, the use of steroidal drugs is becoming more and more controversial, resulting in an increasing need for new and safer anti-inflammatory agents. In theExpand
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Anti-inflammatory activity of gallic acid.
Gallic acid was found to possess antiinflammatory activity towards zymosan-induced acute food pad swelling in mice. In vitro studies on the mode of action of gallic acid revealed that this compoundExpand
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Immunomodulatory and anti-inflammatory activity of Picrorhiza scrophulariiflora.
Extracts of the rhizomes of Picrorhiza scrophulariiflora Pennell (Scrophulariaceae) were investigated for their in vitro and in vivo immunomodulatory properties. Diethyl ether extracts showed potentExpand
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Cyclogossine A: a novel cyclic heptapeptide isolated from the latex of Jatropha gossypifolia.
From the latex of Jatropha gossypifolia L. (Euphorbiaceae) a novel cyclic heptapeptide was isolated, which we named cyclogossine A. A combination of amino acid analysis, FAB mass spectrometry, andExpand
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Antiarthritic activity of the newly developed neutrophil oxidative burst antagonist apocynin.
The plant-phenol 4-hydroxy-3-methoxyacetophenone (trivial name apocynin) is a strong inhibitor of neutrophil superoxide anion (O2-) release in vitro. In vitro the inhibitory effect of apocynin isExpand
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[Arnica montana L].
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An anti-complementary polysaccharide with immunological adjuvant activity from the leaf parenchyma gel of Aloe vera.
The aim of the study is to develop new substances with immunomodulatory activity. To this end, extracts from plants used in traditional medicine are used as starting material. This study deals withExpand
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An ethnopharmacognostic approach to the search for immunomodulators of plant origin.
The search for immunomodulating plant constituents through basic and field inquiries into the literature and practices of traditional Indian medicine is treated. The strategy of data collectingExpand
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