• Publications
  • Influence
Anti-infective potential of natural products: how to develop a stronger in vitro 'proof-of-concept'.
This review provides a number of recommendations that will help to define a more sound 'proof-of-concept' for antibacterial, antifungal, antiviral and antiparasitic potential in natural products. Expand
Structure-activity relationship and classification of flavonoids as inhibitors of xanthine oxidase and superoxide scavengers.
The structure-activity relationship of flavonoids as inhibitors of xanthine oxidase and as scavengers of the superoxide radical, produced by the action of the enzyme xanthines oxidase, was investigated and showed slightly higher inhibitory activity than flavonols. Expand
Correlation between chemical composition and antibacterial activity of essential oils of some aromatic medicinal plants growing in the Democratic Republic of Congo.
The chemical composition of essential oils from 15 aromatic medicinal plant species growing in the Democratic Republic of Congo have been studied and results indicate that all essential oils inhibited the growth of selected bacteria at different extents. Expand
In vitro antiplasmodial activity of extracts and fractions from seven medicinal plants used in the Democratic Republic of Congo.
The in vitro antiplasmodial activity of seven EtOH extracts and twenty fractions from the partition of the initial ethanolic extracts from seven African medicinal plants used in the Democratic Republic of Congo was evaluated and may be related to the presence of terpenes, steroids, coumarins, flavonoids, phenolic acids, lignans, xanthones and anthraquinones. Expand
Antiamoebic and phytochemical screening of some Congolese medicinal plants.
Results from the in vitro antiamoebic activity of some Congolese plant extracts used as antidiarrhoeic in traditional medicine indicated that of 45 plant extracts tested, 35 (77.78%) exhibited anExpand
Screening of hundred Rwandese medicinal plants for antimicrobial and antiviral properties.
A series of 100 Rwandese medicinal plants, used by traditional healers to treat infections, were screened for antibacterial, antifungal and antiviral properties and not less than 27% of the plant species exhibited prominent antiviral Properties against one or more test viruses. Expand
Antimalarial activity of 20 crude extracts from nine African medicinal plants used in Kinshasa, Congo.
Twenty extracts including ten EtOH and ten CH2Cl2 from different parts of nine African medicinal plants used in Congolese traditional medicine for the treatment of malaria, were submitted to aExpand
Phytoestrogens: recent developments.
Since phytoestrogens are structurally very similar to the estrogen 17beta-estradiol, they may exhibit selective estrogen receptor modulating activities, and special attention will be given to the hormonal effects of various isoflavonoids, including genistein, daidzein, coumestrol and equol, several prenylated flavonoid, especially 8-prenylnaringenin, and the stilbene resveratrol. Expand
Plant-derived leading compounds for chemotherapy of human immunodeficiency virus (HIV) infection.
Many compounds of plant origin that inhibit different stages in the replication cycle of human immunodeficiency virus (HIV) have been identified and only a very few of these plant-derived anti-HIV products have been used in a limited number of patients suffering from AIDS. Expand