Clorgyline

Known as: CLORGILINE, Chlorgyline, 2-Propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl- 
An antidepressive agent and monoamine oxidase inhibitor related to PARGYLINE.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The genetic deletion of monoamine oxidase A (MAO A), an enzyme that breaks down the monoamine neurotransmitters norepinephrine… (More)
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2001
2001
[11C]Clorgyline selectively binds to MAO A in the human brain. This contrasts with a recent report that [11C]clorgyline (in… (More)
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Highly Cited
1989
Highly Cited
1989
Parkinson disease is characterized by a major loss (approximately 80% or more) of dopaminergic nigrostriatal neurons and by an… (More)
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Highly Cited
1987
Highly Cited
1987
The regional distributions of monoamine oxidase (MAO) types A and B have been identified in human brain in vivo with… (More)
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Highly Cited
1987
Highly Cited
1987
1. Mice when suspended by the tail will alternate between active attempts to escape and immobility. Immobility like that measured… (More)
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Highly Cited
1984
Highly Cited
1984
1-Methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) causes degeneration of the dopaminergic nigrostriatal pathway in several… (More)
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Highly Cited
1983
Highly Cited
1983
Patients with obsessive-compulsive disorder who met DSM-III criteria and who had been ill for at least one year were studied in a… (More)
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Highly Cited
1981
Highly Cited
1981
A simple model system for the behavioral actions of benzodiazepines is analyzed for its dose-response predictiveness, using… (More)
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1980
1980
The interaction of clorgyline andl-deprenil with the-A and-B forms of human brain monoamine oxidase (MAO) has been studied. Both… (More)
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1979
1979
The antidepressant and other behavioral effects of clorgyline, a preferential inhibitor of monoamine oxidase (MAO) type A, were… (More)
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