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Chimera organism

Known as: Chimera, Chimeras, Chimeric 
Having parts of different origins. In medicine, refers to a person, organ, or tissue that contains cells with different genes than the rest of the… Expand
National Institutes of Health

Related topics

Related topics

10 relations
Animals, TransgenicChimera disorderChimerismFreemartinism
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Broader (1)

Hybrids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Targeted protein degradation: elements of PROTAC design.
Targeted protein degradation using Proteolysis Targeting Chimeras (PROTACs) has emerged as a novel therapeutic modality in drug… Expand
Is this relevant?
Review
2019
Review
2019
Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells
Effective adoptive T cell therapy (ACT) comprises the killing of cancer cells through the therapeutic use of transferred T cells… Expand
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Review
2019
Review
2019
Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges.
Proteolysis targeting chimeras (PROTACs) are heterobifunctional compounds with molecular weights and other properties that lie… Expand
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Review
2019
Review
2019
Induced pluripotent stem cells in disease modelling and drug discovery
The derivation of induced pluripotent stem cells (iPSCs) over a decade ago sparked widespread enthusiasm for the development of… Expand
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Review
2018
Review
2018
The impacts of H. pylori virulence factors on the development of gastroduodenal diseases
Although most H. pylori infectors are asymptomatic, some may develop serious disease, such as gastric adenocarcinoma, gastric… Expand
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Highly Cited
2014
Highly Cited
2014
Chimeric antigen receptor T cells for sustained remissions in leukemia.
BACKGROUND Relapsed acute lymphoblastic leukemia (ALL) is difficult to treat despite the availability of aggressive therapies… Expand
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Highly Cited
2011
Highly Cited
2011
UCHIME improves sensitivity and speed of chimera detection
Motivation: Chimeric DNA sequences often form during polymerase chain reaction amplification, especially when sequencing single… Expand
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Highly Cited
2011
Highly Cited
2011
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.
We designed a lentiviral vector expressing a chimeric antigen receptor with specificity for the B-cell antigen CD19, coupled with… Expand
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Highly Cited
2006
Highly Cited
2006
Greengenes, a Chimera-Checked 16S rRNA Gene Database and Workbench Compatible with ARB
ABSTRACT A 16S rRNA gene database (http://greengenes.lbl.gov ) addresses limitations of public repositories by providing chimera… Expand
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Highly Cited
1998
Highly Cited
1998
A Third-Generation Lentivirus Vector with a Conditional Packaging System
ABSTRACT Vectors derived from human immunodeficiency virus (HIV) are highly efficient vehicles for in vivo gene delivery. However… Expand
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