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Cell Ontogeny

Development of the individual cell, as distinguished from phylogeny, which is evolutionary development of the species.
National Institutes of Health

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AnoikisApoptosisCaspase-Dependent ApoptosisCaspase-Independent Apoptosis

Papers overview

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Highly Cited
1996
Highly Cited
1996
Mature T cell reactivity altered by peptide agonist that induces positive selection
Recent studies have investigated how defined peptides influence T cell development. Using a T cell receptor-transgenic beta2… 
Highly Cited
1995
Highly Cited
1995
The growth response to IL-7 during normal human B cell ontogeny is restricted to B-lineage cells expressing CD34.
The growth of human B cell precursors can be supported by bone marrow (BM) stromal cells and IL-7, but the identity of the… 
Review
1995
Review
1995
Mast cell ontogeny and apoptosis
Abstract The regulation of tissue mast cell number depends both on the rate of production of mast cell precursors from bone… 
Highly Cited
1990
Highly Cited
1990
B-cell differentiation following autologous, conventional, or T-cell depleted bone marrow transplantation: a recapitulation of normal B-cell ontogeny.
The circulating lymphocytes of 88 consecutive patients following autologous, conventional, or T-cell depleted bone marrow… 
Highly Cited
1990
Highly Cited
1990
First T cell receptor alpha gene rearrangements during T cell ontogeny skew to the 5' region of the J alpha locus.
Fetal, neonatal, and early postnatal thymi were assessed for TCR J alpha gene rearrangements. Gene probes spanning the distance… 
Highly Cited
1989
Highly Cited
1989
The expression of T cell receptor-associated proteins during T cell ontogeny in man.
The expression of TCR-associated molecules was examined in human fetal and postnatal tissues. From gestational wk 7 onward in the… 
Highly Cited
1989
Highly Cited
1989
Preferential Expression of VH5 and VH6 Immunoglobulin Genes in Early Human B‐Cell Ontogeny
Analysis of Ig transcripts by dot blot hybridization revealed that VH5 and VH6 RNA first occurred during the 7th week of… 
Highly Cited
1987
Highly Cited
1987
Amplification of human B cell activation by a monoclonal antibody to the B cell-specific antigen CD22, Bp 130/140.
The B cell-specific antigen CD22 is a 130/140-Kd complex and is unique among human B cell antigens, since its surface expression… 
Review
1983
Review
1983
T-cell function and specificity in athymic mice
Highly Cited
1980
Highly Cited
1980
Mouse pre-B cells synthesize and secrete μ heavy chains but not light chains
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