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Cell Ontogeny

Development of the individual cell, as distinguished from phylogeny, which is evolutionary development of the species.
National Institutes of Health

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AnoikisApoptosisCaspase-Dependent ApoptosisCaspase-Independent Apoptosis

Papers overview

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Highly Cited
2004
Highly Cited
2004
Cutting Edge: The Ontogeny and Function of Va14Ja18 Natural T Lymphocytes Require Signal Processing by Protein Kinase Cθ and NF-κB1
The rapid and robust immunoregulatory cytokine response of Va14Ja18 natural T (iNKT) cells to glycolipid Ags determines their… 
Review
2001
Review
2001
Ontogeny and Expansion of Human Natural Killer Cells: Clinical Implications
Our knowledge of NK cells and their critical role in the innate immune system has increased enormously since their discovery… 
Highly Cited
1990
Highly Cited
1990
First T cell receptor alpha gene rearrangements during T cell ontogeny skew to the 5' region of the J alpha locus.
Fetal, neonatal, and early postnatal thymi were assessed for TCR J alpha gene rearrangements. Gene probes spanning the distance… 
1989
1989
T-cell ontogeny after autologous bone marrow transplantation: failure to synthesize interleukin-2 (IL-2) and lack of CD2- and CD3-mediated proliferation by both CD4- and CD8+ cells even in the…
T cells generated during a second round of ontogeny after autologous bone marrow transplantation (ABMT) represent a unique model… 
Highly Cited
1987
Highly Cited
1987
Amplification of human B cell activation by a monoclonal antibody to the B cell-specific antigen CD22, Bp 130/140.
The B cell-specific antigen CD22 is a 130/140-Kd complex and is unique among human B cell antigens, since its surface expression… 
Highly Cited
1987
Highly Cited
1987
Identification and sequence of a fourth human T cell antigen receptor chain
Thymus-derived lymphocytes (T cells) use clonally distributed antigen receptors to recognize peptide fragments associated with… 
Highly Cited
1985
Highly Cited
1985
Expression of genes of the T-cell antigen receptor complex in precursor thymocytes
The antigen receptor on Tlymphocytes has recently been characterized as a heterodimeric, transmembrane glycoprotein consisting of… 
Review
1983
Review
1983
T-cell function and specificity in athymic mice.
Highly Cited
1980
Highly Cited
1980
Mouse pre-B cells synthesize and secrete μ heavy chains but not light chains
1976
1976
B-cell ontogeny in the chicken.
We conclude that our data are most consistent with the hypothesis that individual bursal stem cells give rise to multiple clones… 
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