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Anoikis

Known as: Detachment-Induced Cell Death, suspension induced apoptosis, Suspension-Induced Apoptosis 
Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells… 
National Institutes of Health

Related topics

Related topics

7 relations
Cell Death Signaling ProcessCell OntogenyThymic T-Cell Selectionaspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Nature's necrosis factor when associated with erythrocytes may not only explain the surprises in lung cancer metastases but also suggest target therapy.
Review
2011
Review
2011
Stress Influences on Anoikis
It long has been suspected that psychosocial factors affect cancer development and progression. Although the connections between… 
2008
2008
Cleavage of focal adhesion kinase is an early marker and modulator of oxidative stress-induced apoptosis.
2008
2008
Tumorigenicity of IL-1α– and IL-1β–Deficient Fibrosarcoma Cells
Analyzing the growth of fibrosarcoma lines derived from IL-1α-, IL-1β- , or IL-1αβ-knockout (-/-) mice in the immunocompetent… 
2007
2007
Cytotoxic effects of 2-arylbenzofuran phytoestrogens on human cancer cells: Modulation by adrenal and gonadal steroids
Highly Cited
2003
Highly Cited
2003
The anti-apoptotic role of PPARβ contributes to efficient skin wound healing
2002
2002
Angiostatin induces intracellular acidosis and anoikis in endothelial cells at a tumor-like low pH.
Angiostatin inhibits angiogenesis by binding to endothelial cells (ECs) lining the vasculature of growing tumors. These cells are… 
Highly Cited
2001
Highly Cited
2001
Induction of anoikis and suppression of human ovarian tumor growth in vivo by down-regulation of Bcl-X(L).
Normal or immortal epithelial cells are sensitive to a form of apoptosis, commonly referred to as anoikis, which is induced by… 
2001
2001
Tyrosine kinase-dependent, phosphatidylinositol 3'-kinase, and mitogen-activated protein kinase-independent signaling pathways prevent lung adenocarcinoma cells from anoikis.
Normal epithelial cells are anchorage-dependent. Detachment of normal epithelial cells from their substratum causes apoptosis… 
1999
1999
Collateral expression of proangiogenic and tumorigenic properties in intestinal epithelial cell variants selected for resistance to anoikis.
Although in vitro anchorage-independent growth is widely used as a marker of cell transformation, the biological implications of… 
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