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Anoikis

Known as: Detachment-Induced Cell Death, suspension induced apoptosis, Suspension-Induced Apoptosis 
Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells… 
National Institutes of Health

Related topics

Related topics

7 relations
Cell Death Signaling ProcessCell OntogenyThymic T-Cell Selectionaspects of radiation effects

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Norcantharidin is a small-molecule synthetic compound with anti-angiogenesis effect.
Highly Cited
2006
Highly Cited
2006
The RhoA/ROCK-I/MLC pathway is involved in the ethanol-induced apoptosis by anoikis in astrocytes
Anoikis is a programmed cell death induced by loss of anchorage that is involved in tissue homeostasis and disease. Ethanol is an… 
Highly Cited
2006
Highly Cited
2006
Urokinase Signaling through Its Receptor Protects against Anoikis by Increasing BCL-xL Expression Levels*
The acquired capabilities of resistance to apoptotic cell death and tissue invasion are considered to be obligate steps in tumor… 
Review
2005
Review
2005
Selective evolutionary pressure from the tissue microenvironment drives tumor progression.
Highly Cited
2004
Highly Cited
2004
Squamous Cell Carcinoma Cell Aggregates Escape Suspension-induced, p53-mediated Anoikis
Resistance to anoikis, or apoptosis triggered by detachment from the extracellular matrix (ECM), lengthens the survival of… 
Highly Cited
2003
Highly Cited
2003
The anti-apoptotic role of PPARβ contributes to efficient skin wound healing
Highly Cited
2002
Highly Cited
2002
Hepatocyte growth factor inhibits anoikis in head and neck squamous cell carcinoma cells by activation of ERK and Akt signaling independent of NFkappa B.
Hepatocyte growth factor (HGF), also known as a scatter factor, regulates a variety of biological activities including cell… 
Highly Cited
2001
Highly Cited
2001
Apoptotic signaling during initiation of detachment-induced apoptosis ("anoikis") of primary human intestinal epithelial cells.
Apoptosis after the loss of cell anchorage--"anoikis"--plays an important role in the life cycle of adherent cells. Furthermore… 
Highly Cited
2001
Highly Cited
2001
Induction of anoikis and suppression of human ovarian tumor growth in vivo by down-regulation of Bcl-X(L).
Normal or immortal epithelial cells are sensitive to a form of apoptosis, commonly referred to as anoikis, which is induced by… 
Highly Cited
1998
Highly Cited
1998
Insulin‐like growth factor‐I‐mediated survival from Anoikis: Role of cell aggregation and focal adhesion kinase
Anoikis is a form of cell death that occurs when cells are denied attachment to the extra‐cellular matrix. Using p6 cells, that… 
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