Anoikis

Known as: Detachment-Induced Cell Death, suspension induced apoptosis, Suspension-Induced Apoptosis 
Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells… (More)
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Anoikis is a programmed cell death induced upon cell detachment from extracellular matrix, behaving as a critical mechanism in… (More)
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Highly Cited
2012
Highly Cited
2012
Cell attachment to the extracellular matrix (ECM) is crucial to cell physiology such as polarity, motility, and proliferation. In… (More)
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Highly Cited
2011
Highly Cited
2011
Anoikis (or cell-detachment-induced apoptosis) is a self-defense strategy that organisms use to eliminate 'misplaced' cells, i.e… (More)
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Highly Cited
2006
Highly Cited
2006
Metastatic disease is the primary cause of death in breast cancer, the most common malignancy in Western women. Loss of E… (More)
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Highly Cited
2004
Highly Cited
2004
Metastasis is a major factor in the malignancy of cancers, and is often responsible for the failure of cancer treatment. Anoikis… (More)
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Highly Cited
2003
Highly Cited
2003
Epithelial cells must adhere to the extracellular matrix (ECM) for survival, as detachment from matrix triggers apoptosis or… (More)
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Review
2001
Review
2001
Anoikis is defined as apoptosis that is induced by inadequate or inappropriate cell-matrix interactions. It is involved in a wide… (More)
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Highly Cited
2001
Highly Cited
2001
Bcl-2 family members bearing only the BH3 domain are essential inducers of apoptosis. We identified a BH3-only protein, Bmf, and… (More)
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Review
1997
Review
1997
The loss of integrin-mediated cell-matrix contact induces apoptosis ('anoikis') in certain cell types. Recently it has been shown… (More)
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Highly Cited
1994
Highly Cited
1994
Cell-matrix interactions have major effects upon phenotypic features such as gene regulation, cytoskeletal structure… (More)
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