Cartilage oligomeric matrix protein:ACnc:Pt:Ser:Qn:IA

Known as: ???????? ??????????? ?????????? ???????:??????????:??????:???:?????:IA, Proteina oligomerica matrice cartilaginea:ACnc:Pt:Siero:Qn:IA, Proteína oligomérica de matriz del cartílago (COMP):Concentración arbitraria:Punto temporal:Suero:Qn:IA 
 
National Institutes of Health

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ACncCartilage Oligomeric Matrix ProteinImmunoassay methodProteins
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Papers overview

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2014
2014
Specific targeting of tau oligomers in Htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds.
Neurodegenerative disease is one of the greatest health crises in the world and as life expectancy rises, the number of people… (More)
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Highly Cited
2013
Highly Cited
2013
A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss.
Alzheimer's disease (AD) is hallmarked by amyloid plaques, neurofibrillary tangles, and widespread cortical neuronal loss (Selkoe… (More)
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2013
2013
Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.
Human apolipoprotein E (apoE) isoforms may differentially modulate amyloid-β (Aβ) levels. Evidence suggests physical interactions… (More)
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2013
2013
Abnormal interaction of oligomeric amyloid-β with phosphorylated tau: implications to synaptic dysfunction and neuronal damage.
Alzheimer's disease (AD) is a progressive neurodegenerative mental illness characterized by memory loss, multiple cognitive… (More)
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Highly Cited
2011
Highly Cited
2011
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease.
Increasing evidence suggests that the accumulation of amyloid beta (Aβ) in synapses and synaptic mitochondria causes synaptic… (More)
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2011
2011
Brain oligomeric β-amyloid but not total amyloid plaque burden correlates with neuronal loss and astrocyte inflammatory response in amyloid precursor protein/tau transgenic mice.
It has long been assumed that β-amyloid (Aβ) had to assemble into fibrillar amyloid plaques to exert its neurotoxic effects in… (More)
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2011
2011
Durable, self-healing superhydrophobic and superoleophobic surfaces from fluorinated-decyl polyhedral oligomeric silsesquioxane and hydrolyzed fluorinated alkyl silane.
Super-liquid-repellent surfaces have attracted much attention in both scientific and industrial areas. They are often deemed… (More)
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Highly Cited
2010
Highly Cited
2010
Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease-linked APPswe/PS1DeltaE9 mice.
Experience in complex environments induces numerous forms of brain plasticity, improving structure and function. It has been long… (More)
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Highly Cited
2009
Highly Cited
2009
Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques.
Synapse loss correlates with a cognitive decline in Alzheimer's disease (AD), but whether this is caused by fibrillar deposits… (More)
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Highly Cited
2007
Highly Cited
2007
Oligomeric amyloid decreases basal levels of brain-derived neurotrophic factor (BDNF) mRNA via specific downregulation of BDNF transcripts IV and V in differentiated human neuroblastoma cells.
Alzheimer's disease (AD) is a senile dementia characterized by amyloid plaques, neurofibrillary tangles, and synaptic and cell… (More)
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