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The Chemistry and Biology of Alkannin, Shikonin, and Related Naphthazarin Natural Products.
Wound healing properties of plant extracts that contain the naphthoquinone natural products alkannin (1) and shikonin (2) have been known for many centuries. More recently, the biological propertiesExpand
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Radical scavenging activity of various extracts and fractions of sweet orange peel (Citrus sinensis)
Abstract Seven different extracts, fractions and residues of Navel sweet orange (Citrus sinensis) peel were evaluated for their radical scavenging activity by the DPPH and luminol inducedExpand
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Radical scavenging activity of Crocus sativus L. extract and its bioactive constituents
Radical scavenging activity is involved in aging processes, antiinflammatory, anticancer and wound healing activity. Hence, in the present study the DPPH radical scavenging activity of a naturalExpand
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Alkannins and shikonins: a new class of wound healing agents.
Alkannins and Shikonins (A/S) are chiral-pairs of naturally occurring isohexenylnaphthazarins. They are found in the external layer of the roots of at least a hundred and fifty species that belongExpand
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Antioxidant activity of natural resins and bioactive triterpenes in oil substrates
Abstract Natural resins that possess biological properties (Pistacia lentiscus var. Chia, Commiphora myrrh, Boswellia serrata and Gum storax) and the bioactive triterpenes (oleanolic acid and ursolicExpand
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Pharmacophore-driven identification of PPARγ agonists from natural sources
TLDR
In a search for more effective and safe anti-diabetic compounds, we developed a pharmacophore model based on partial agonists of PPARγ. Expand
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Inhibitory activity of minor polyphenolic and nonpolyphenolic constituents of olive oil against in vitro low-density lipoprotein oxidation.
The minor polyphenolic and nonpolyphenolic constituents of olive oil were examined, in various doses, against copper ion-induced low-density lipoprotein (LDL) oxidation and were found, in optimalExpand
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Gas chromatographic–mass spectroscopic analysis of the acidic triterpenic fraction of mastic gum
Abstract The acidic fraction of mastic gum, the resin of Pistacia lentiscus L. var. Chia , was analyzed using GC–MS. Ten triterpenoid acids – three already known – were tentatively identified asExpand
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Analysis of antioxidant compounds in sweet orange peel by HPLC-diode array detection-electrospray ionization mass spectrometry.
HPLC-diode array detection-electrospray ionization mass spectrometry was used to determine qualitatively and quantitatively the flavonoid content of several fractions and residues of extracts ofExpand
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Chemotaxonomy of the Greek Species of Sideritis I. Components of the volatile fraction of Sideritis raeseri ssp. raeseri
As it has been reported (3), we have started studying the Greek species of the genus Sideritis, section Empedoclia, from a biosystematic point of view. Furthermore we are studying the chemicalExpand
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