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Carbolines

Known as: Carbolines [Chemical/Ingredient], Pyrido(4,3-b)Indoles, carboline 
A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these… Expand
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (46)

12,34-oxamanzamine E2,9-dimethyl-beta-carbolinium3-aminonorharman3-methylcanthin-5,6-dione
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In Bloodagonistsantagonists & inhibitorschemical synthesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria
The antiplasmodial activity of a series of spirotetrahydro β-carbolines is described. Racemic spiroazepineindole (1) was… Expand
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Highly Cited
2010
Highly Cited
2010
Spiroindolones, a Potent Compound Class for the Treatment of Malaria
Antimalarial Drug Candidate Spiroindolones were discovered as promising antimalarial drug candidates through a high-throughput… Expand
Highly Cited
2010
Highly Cited
2010
beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO).
Peganum harmala L. is a multipurpose medicinal plant increasingly used for psychoactive recreational purposes (Ayahuasca analog… Expand
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Review
2004
Review
2004
Exposure to beta-carbolines norharman and harman.
  • W. Pfau, K. Skog
  • Journal of chromatography. B, Analytical…
  • 2004
    • Corpus ID: 33497743
The aromatic beta-carbolines norharman and harman have been implicated in a number of human diseases including Parkinson's… Expand
Highly Cited
2003
Highly Cited
2003
Novel IKK inhibitors: β-carbolines
Abstract Inhibitors of IκB kinase (IKK) have long been sought as specific regulators of NF-κB. A screening effort of the… Expand
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Review
1996
Review
1996
Oxidative stress and the pathogenesis of Parkinson's disease
  • Peter Jenner, C. Olanow
  • Neurology
  • 1996
    • Corpus ID: 8189310
Current concepts of the pathogenesis of Parkinson's disease (PD) center on the formation of reactive oxygen species and the onset… Expand
Highly Cited
1996
Highly Cited
1996
Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys.
The selective activation of the prefrontal cortical dopamine system by mild stress can be mimicked by anxiogenic beta-carbolines… Expand
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Highly Cited
1984
Highly Cited
1984
Monoamine oxidase inhibitors in South American hallucinogenic plants: tryptamine and beta-carboline constituents of ayahuasca.
Ayahuasca is a hallucinogenic beverage derived by boiling the bark of the Malpighiaceous liana Banisteriopsis caapi together with… Expand
Highly Cited
1983
Highly Cited
1983
Isolation, characterization, and purification to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors.
A brain polypeptide termed diazepam-binding inhibitor (DBI) and thought to be chemically and functionally related to the… Expand
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Highly Cited
1976
Highly Cited
1976
Radioimmunoassay of serum concentrations of melatonin in sheep exposed to different lighting regimens.
A specific and sensitive double-antibody radioimmunoassay for melatonin (N-acetyl-5-methoxytryptamine) has been developed… Expand
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