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Carbolines

Known as: Carbolines [Chemical/Ingredient], Pyrido(4,3-b)Indoles, carboline 
A group of pyrido-indole compounds. Included are any points of fusion of pyridine with the five-membered ring of indole and any derivatives of these… Expand
National Institutes of Health

Related topics

Related topics

50 relations

Narrower (46)

12,34-oxamanzamine E2,9-dimethyl-beta-carbolinium3-aminonorharman3-methylcanthin-5,6-dione
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In Bloodagonistsantagonists & inhibitorschemical synthesis

Papers overview

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Highly Cited
2010
Highly Cited
2010
Spirotetrahydro β-Carbolines (Spiroindolones): A New Class of Potent and Orally Efficacious Compounds for the Treatment of Malaria
The antiplasmodial activity of a series of spirotetrahydro β-carbolines is described. Racemic spiroazepineindole (1) was… Expand
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Highly Cited
2010
Highly Cited
2010
Spiroindolones, a Potent Compound Class for the Treatment of Malaria
Antimalarial Drug Candidate Spiroindolones were discovered as promising antimalarial drug candidates through a high-throughput… Expand
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Highly Cited
2010
Highly Cited
2010
beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO).
Peganum harmala L. is a multipurpose medicinal plant increasingly used for psychoactive recreational purposes (Ayahuasca analog… Expand
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Highly Cited
2010
Highly Cited
2010
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents.
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder with multifactorial causes that requires multitargeted… Expand
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Highly Cited
2007
Highly Cited
2007
Antioxidant properties of beta-carboline alkaloids are related to their antimutagenic and antigenotoxic activities.
The beta-carboline alkaloids found in medical plants and in a variety of foods, beverages and cigarette smoke have a range of… Expand
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Review
2004
Review
2004
Exposure to beta-carbolines norharman and harman.
The aromatic beta-carbolines norharman and harman have been implicated in a number of human diseases including Parkinson's… Expand
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Highly Cited
2003
Highly Cited
2003
Novel IKK inhibitors: β-carbolines
Inhibitors of IκB kinase (IKK) have long been sought as specific regulators of NF-κB. A screening effort of the endogenous IKK… Expand
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Highly Cited
2003
Highly Cited
2003
Cytotoxic and antimalarial beta-carboline alkaloids from the roots of Eurycoma longifolia.
Three new [n-pentyl beta-carboline-1-propionate (1), 5-hydroxymethyl-9-methoxycanthin-6-one (2), and 1-hydroxy-9-methoxycanthin-6… Expand
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Review
1996
Review
1996
Oxidative stress and the pathogenesis of Parkinson's disease
Current concepts of the pathogenesis of Parkinson's disease (PD) center on the formation of reactive oxygen species and the onset… Expand
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Highly Cited
1984
Highly Cited
1984
Monoamine oxidase inhibitors in South American hallucinogenic plants: tryptamine and beta-carboline constituents of ayahuasca.
Ayahuasca is a hallucinogenic beverage derived by boiling the bark of the Malpighiaceous liana Banisteriopsis caapi together with… Expand
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