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Calcineurin
Known as:
Protein Phosphatase-2B
, Protein Phosphatase 2B
, Calcineurin [Chemical/Ingredient]
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Ubiquitous heterodimeric human Calcineurin is Ca(2+)/calmodulin-regulated protein phosphatase involved in many biologic activities as a modifier of…
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National Institutes of Health
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Related topics
Related topics
26 relations
Brain
Calcineurin activity
Dephosphorylation
In Blood
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Narrower (9)
Cabin1 protein, mouse
Calcineurin A
Calcineurin B
PBO-1 protein, C elegans
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Broader (2)
Calmodulin-Binding Proteins
Phosphoric Monoester Hydrolases
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria
G. Cereghetti
,
A. Stangherlin
,
+4 authors
L. Scorrano
Proceedings of the National Academy of Sciences
2008
Corpus ID: 21134610
Changes in mitochondrial morphology that occur during cell cycle, differentiation, and death are tightly regulated by the balance…
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Review
2003
Review
2003
Transcriptional regulation by calcium, calcineurin, and NFAT.
P. Hogan
,
Lin Chen
,
J. Nardone
,
A. Rao
Genes & development
2003
Corpus ID: 1705257
The NFAT family of transcription factors encompasses five proteins evolutionarily related to the Rel/NF B family (Chytil and…
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Review
2000
Review
2000
Calcineurin: form and function.
F. Rusnak
,
P. Mertz
Physiological reviews
2000
Corpus ID: 5029385
Calcineurin is a eukaryotic Ca(2+)- and calmodulin-dependent serine/threonine protein phosphatase. It is a heterodimeric protein…
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Highly Cited
1999
Highly Cited
1999
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD.
H. G. Wang
,
N. Pathan
,
+7 authors
John Calvin Reed
Science
1999
Corpus ID: 32140709
The Ca2+-activated protein phosphatase calcineurin induces apoptosis, but the mechanism is unknown. Calcineurin was found to…
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Highly Cited
1998
Highly Cited
1998
A calcineurin-dependent transcriptional pathway controls skeletal muscle fiber type.
E. Chin
,
E. Olson
,
+7 authors
R. S. Williams
Genes & development
1998
Corpus ID: 12226462
Slow- and fast-twitch myofibers of adult skeletal muscles express unique sets of muscle-specific genes, and these distinctive…
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Highly Cited
1998
Highly Cited
1998
A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy
J. Molkentin
,
Jian-rong Lu
,
+5 authors
E. Olson
Cell
1998
Corpus ID: 16574424
Review
1998
Review
1998
Regulation of the Calmodulin-stimulated Protein Phosphatase, Calcineurin*
C. Klee
,
H. Ren
,
Xutong Wang
The Journal of Biological Chemistry
1998
Corpus ID: 26183786
The role of protein phosphatases in the regulation of cellular processes is now well established (1, 2). Calcineurin (also called…
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Highly Cited
1995
Highly Cited
1995
Crystal structures of human calcineurin and the human FKBP12–FK506–calcineurin complex
C. Kissinger
,
H. Parge
,
+14 authors
J. E. Villafranca
Nature
1995
Corpus ID: 4337105
CALCINEURIN (CaN) is a calcium- and ca 1modulin-dependent protein serine/threonine phosphatase which is critical for several…
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Review
1992
Review
1992
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
N. Clipstone
,
G. Crabtree
Nature
1992
Corpus ID: 4363653
THE immunosuppressive drugs cyclosporin A (CsA) and FKS06 both interfere with a Ca2+-sensitive T-cell signal transduction…
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Highly Cited
1991
Highly Cited
1991
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes
Jun S. Liu
,
J. Farmer
,
W. Lane
,
J. Friedman
,
I. Weissman
,
S. Schreiber
Cell
1991
Corpus ID: 22094672
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