Calcineurin

Known as: Protein Phosphatase-2B, Protein Phosphatase 2B, Calcineurin [Chemical/Ingredient] 
Ubiquitous heterodimeric human Calcineurin is Ca(2+)/calmodulin-regulated protein phosphatase involved in many biologic activities as a modifier of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1979-2017
05010019792017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Changes in mitochondrial morphology that occur during cell cycle, differentiation, and death are tightly regulated by the balance… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2004
Highly Cited
2004
Sustained calcium signaling induces a state of anergy or antigen unresponsiveness in T cells, mediated through calcineurin and… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The azole antifungal fluconazole possesses only fungistatic activity in Candida albicans and, therefore, this human pathogen is… (More)
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Adult skeletal muscle fibers can be categorized into fast and slow twitch subtypes based on specialized contractile and metabolic… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The Ca2+-activated protein phosphatase calcineurin induces apoptosis, but the mechanism is unknown. Calcineurin was found to… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Molecular signaling pathways linking increases in skeletal muscle usage to alterations in muscle size have not been identified… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Cyclosporin A (CsA) and FK506 are antimicrobial, immunosuppressive natural products that inhibit signal transduction. In T cells… (More)
  • table II
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
Calcineurin is a conserved Ca2+/calmodulin-dependent protein phosphatase that plays a critical role in Ca2+ signaling. We… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1992
Highly Cited
1992
Antigen recognition by the T-cell receptor (TCR) initiates events including lymphokine gene transcription, particularly… (More)
Is this relevant?
Highly Cited
1979
Highly Cited
1979
The inhibitory protein that binds calmodulin and thus prevents activation of several Ca2+-dependent enzymes by calmodulin is… (More)
  • figure 2
  • figure 1
  • table 1
  • figure 3
Is this relevant?