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Calcineurin activity

Known as: calcineurin, protein phosphatase type 2B activity 
 
National Institutes of Health

Related topics

Related topics

3 relations
Calcineurin

Broader (2)

calcium-dependent protein serine/threonine phosphatase activityprotein serine/threonine phosphatase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Measurement of calcineurin activity in peripheral blood mononuclear cells by ultra-high performance liquid chromatography-tandem mass spectrometry. Renal transplant recipients application…
BACKGROUND Therapeutic drug monitoring of calcineurin inhibitor, tacrolimus (TAC), is routinely used in post-transplantation… Expand
2018
2018
High Calcineurin Inhibitor Intra Patient Variability is Associated with Early Renal Allograft Inflammation, Chronicity and Loss
High CNI IPV has been associated with poor kidney allograft outcomes, albeit in small limited studies.We evaluated effect of CNI… Expand
2015
2015
Enzymatic and thermodynamic analysis of calcineurin inhibition by RCAN1.
Calcineurin (CN) is the target of the immunophilin-immunosuppressant complex, cyclophilin/cyclosporin A (CyP/CsA). RCAN1 has… Expand
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2014
2014
Population PKPD of voclosporin in renal allograft patients
The aims of this population‐pharmacokinetic/pharmacodynamic (POP‐PKPD) analysis of voclosporin in renal allograft patients were… Expand
2013
2013
Assessment of immune function in Down syndrome patients
In Down syndrome (DS), trisomy 21 leads to overexpression of gene coding for specific enzymes. This overexpression translates… Expand
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2008
2008
Prevention of isoproterenol-induced cardiac hypertrophy by eugenol, an antioxidant
Recent reports on the involvement of calcineurin in cardiac hypertrophy and its susceptibility to free radicals, prompted us to… Expand
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2008
2008
Pharmacokinetic-Pharmacodynamic Assessment of Tacrolimus in Liver-Transplant Recipients during the Early Post-Transplantation Period
During the early post-transplantation period, the limitations of monitoring current tacrolimus dose with classic pharmacokinetics… Expand
Highly Cited
2004
Highly Cited
2004
Stimulation of calcineurin signaling attenuates the dystrophic pathology in mdx mice.
Utrophin has been studied extensively in recent years in an effort to find a cure for Duchenne muscular dystrophy. In this… Expand
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2004
2004
New concepts in cyclosporine pharmacokinetic and dynamic monitoring: the impact of concomitant immunosuppression on target C2 concentrations.
BACKGROUND There is a correlation between cyclosporine (CsA) pharmacokinetics (PK) and pharmacodynamics (PD), especially 2 hours… Expand
Highly Cited
2003
Highly Cited
2003
Pharmacodynamic approach to immunosuppressive therapies using calcineurin inhibitors and mycophenolate mofetil.
BACKGROUND Graft survival depends on adequate immunosuppression. To evaluate the effect on the immune system of immunosuppressive… Expand
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