Skip to search formSkip to main contentSkip to account menu

CRK protein, human

Known as: Adapter Molecule CRK, P38, v-crk sarcoma virus CT10 oncogene homolog (avian) protein, human 
Adapter molecule crk (304 aa, ~34 kDa) is encoded by the human CRK gene. This protein is involved in the modulation of signal transduction.
National Institutes of Health

Related topics

Related topics

20 relations
Adaptor Signaling Protein GeneCRK geneCRK wt AlleleCXCR4 Signaling Pathway

Broader (1)

proto-oncogene protein c-crk

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
A role for the Myoblast city homologues Dock1 and Dock5 and the adaptor proteins Crk and Crk-like in zebrafish myoblast fusion
Myoblast fusion follows a defined sequence of events that is strikingly similar in vertebrates and invertebrates. Genetic… 
Highly Cited
2006
Highly Cited
2006
Rap1-Mediated Activation of Extracellular Signal-Regulated Kinases by Cyclic AMP Is Dependent on the Mode of Rap1 Activation
ABSTRACT Like other small G proteins of the Ras superfamily, Rap1 is activated by distinct guanine nucleotide exchange factors… 
Highly Cited
2004
Highly Cited
2004
Roles played by a subset of integrin signaling molecules in cadherin-based cell–cell adhesion
Integrins can intercommunicate with cadherins. Here, we examined their possible relationship by use of small interfering RNA… 
Highly Cited
2004
Highly Cited
2004
Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells
The chemokine-CXCL12 and its receptor, CXCR4, have recently been shown to play an important role in regulating the directional… 
Review
2003
Review
2003
T-cell integrins: more than just sticking points
T cells use integrins in essentially all of their functions. They use integrins to migrate in and out of lymph nodes and… 
Highly Cited
2002
Highly Cited
2002
APS Facilitates c-Cbl Tyrosine Phosphorylation and GLUT4 Translocation in Response to Insulin in 3T3-L1 Adipocytes
ABSTRACT APS is a Cbl-binding protein that is tyrosine phosphorylated by the insulin receptor kinase. Insulin-stimulated… 
Highly Cited
1998
Highly Cited
1998
The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway.
c-Jun N-terminal kinases (JNKs) are potently activated by a number of cellular stimuli. Small GTPases, in particular Rac, are… 
Review
1997
Review
1997
Focal adhesion kinase in integrin signaling.
Highly Cited
1996
Highly Cited
1996
Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases
Integrin-mediated cell adhesion triggers intracellular signaling cascades, including tyrosine phosphorylation of intracellular… 
Highly Cited
1996
Highly Cited
1996
p130Cas, a Substrate Associated with v-Src and v-Crk, Localizes to Focal Adhesions and Binds to Focal Adhesion Kinase*
p130Cas (rk ssociated ubstrate) has the structural characteristics of an adapter protein, containing multiple consensus SH2… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)