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CRK gene

Known as: V-CRK AVIAN SARCOMA VIRUS CT10 ONCOGENE HOMOLOG, ONCOGENE CRK, v-CRK Sarcoma Virus CT10 Oncogene Homolog (Avian) Gene 
This gene is involved in cellular signal transduction and plays a role in transformation.
National Institutes of Health

Related topics

Related topics

3 relations
CRK protein, humanSignal Transduction

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CRK wt Allele

Papers overview

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Highly Cited
2014
Highly Cited
2014
The Arabidopsis thaliana cysteine-rich receptor-like kinases CRK6 and CRK7 protect against apoplastic oxidative stress.
Highly Cited
2002
Highly Cited
2002
Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold
Initiation of cell migration requires morphological polarization with formation of a dominant leading pseudopodium and rear… 
Highly Cited
2001
Highly Cited
2001
Recruitment of Cytoskeletal and Signaling Proteins to Enteropathogenic and Enterohemorrhagic Escherichia coli Pedestals
ABSTRACT Enteropathogenic Escherichia coli (EPEC) is a human pathogen that attaches to intestinal epithelial cells and causes… 
Highly Cited
1998
Highly Cited
1998
The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway.
c-Jun N-terminal kinases (JNKs) are potently activated by a number of cellular stimuli. Small GTPases, in particular Rac, are… 
Highly Cited
1996
Highly Cited
1996
Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.
Src homology 3 (SH3) domains are conserved protein modules 50-70 amino acids long found in a variety of proteins with important… 
Highly Cited
1996
Highly Cited
1996
Direct Binding of C-terminal Region of p130 to SH2 and SH3 Domains of Src Kinase (*)
p130 is a major tyrosine-phosphorylated protein that tightly binds v-Crk in v-crk-transformed cells and v-Src in v-src… 
Highly Cited
1996
Highly Cited
1996
Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.
To understand how protein-protein interactions mediated by the Src-SH3 domain affect c-Src signaling, we screened for proteins… 
Highly Cited
1996
Highly Cited
1996
Src kinase plays an essential role in integrin-mediated tyrosine phosphorylation of Crk-associated substrate p130Cas.
A novel signaling molecule p130Cas has been shown to undergo tyrosine phosphorylation in response to integrin-mediated cell… 
Review
1994
Review
1994
SH2 and SH3 domains as molecular adhesives: the interactions of Crk and Abl.
Highly Cited
1990
Highly Cited
1990
Src homology region 2 domains direct protein-protein interactions in signal transduction.
Cytoplasmic proteins that regulate signal transduction or induce cellular transformation, including cytoplasmic protein-tyrosine… 
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