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CRK gene

Known as: V-CRK AVIAN SARCOMA VIRUS CT10 ONCOGENE HOMOLOG, ONCOGENE CRK, v-CRK Sarcoma Virus CT10 Oncogene Homolog (Avian) Gene 
This gene is involved in cellular signal transduction and plays a role in transformation.
National Institutes of Health

Related topics

Related topics

3 relations
CRK protein, humanSignal Transduction

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CRK wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Abl knockout differentially affects p130 Crk-associated substrate, vinculin, and paxillin in blood vessels of mice.
Actin polymerization has recently emerged as an important cellular process that regulates smooth muscle contraction. Abelson… 
2002
2002
Evidence for CRK3 participation in the cell division cycle of Trypanosoma cruzi.
Highly Cited
2001
Highly Cited
2001
Evidence for a Conserved Role for CrkII and Rac in Engulfment of Apoptotic Cells*
Apoptosis or programmed cell death occurs in multicellular organisms throughout life. The removal of apoptotic cells by… 
2001
2001
T Cell Regulation of p62 dok (Dok1) Association with Crk-L*
In addition to engagement of the T cell receptor-CD3 complex, T lymphocytes can be activated by a variety of cell surface… 
2000
2000
The Association of CRKII with C3G Can be Regulated by Integrins and Defines a Novel Means to Regulate the Mitogen-activated Protein Kinases*
In studies to define mechanisms of ERK activation in Chinese hamster ovary cells, we have observed an inverse correlation between… 
1998
1998
Stage-specific activity of the Leishmania major CRK3 kinase and functional rescue of a Schizosaccharomyces pombe cdc2 mutant.
1997
1997
The BCR/ABL oncogene alters interaction of the adapter proteins CRKL and CRK with cellular proteins
The Philadelphia chromosome translocation generates a chimeric oncogene, BCR/ABL, which causes chronic myelogenous leukemia (CML… 
Highly Cited
1996
Highly Cited
1996
Tyrosine-phosphorylated Cbl binds to Crk after T cell activation.
Crk is a Src homology 2 (SH2)/Src homology 3 (SH3)-containing adapter protein that has been implicated in intracellular signaling… 
Highly Cited
1995
Highly Cited
1995
The SH3 Domain of Crk Binds Specifically to a Conserved Proline-rich Motif in Eps15 and Eps15R (*)
The Crk protein belongs to the family of proteins consisting of mainly Src homology 2 and 3 (SH2 and SH3) domains. These proteins… 
1993
1993
Structural requirement of CRK SH2 region for binding to phosphotyrosine-containing proteins. Evidence from reactivity to monoclonal antibodies.
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