FAQ

CD44 Antigens

Known as: Hyaluronan-Binding Protein, CD44, Chondroitin Sulfate Proteoglycan 8 
Acidic sulfated integral membrane glycoproteins expressed in several alternatively spliced and variable glycosylated forms on a wide variety of cell… (More)

Topic mentions per year

Topic mentions per year

1988-2018
010020030019882018

Related topics

Related topics

11 relations
Blood Group AntigensCD44 geneIn Bloodadministration & dosage
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Broader (1)

CD Antigens

Narrower (3)

CD44 protein, humanCD44, keratinocyteCD44S antigen

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
CD44 Antigens
physiological aspects
Blood Group Antigens
CD44 protein, human
CD Antigens
CD44 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy.
BACKGROUND Tumorigenic breast cancer cells that express high levels of CD44 and low or undetectable levels of CD24 (CD44(>)/CD24… (More)
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Highly Cited
2008
Highly Cited
2008
CD44 is of functional importance for colorectal cancer stem cells.
PURPOSE Both CD44 and CD133 were reported as putative markers for isolating colorectal cancer stem cells (CSC). It remains to be… (More)
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Highly Cited
2008
Highly Cited
2008
Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression
The p53 tumor suppressor is a key mediator of cellular responses to various stresses. Here, we show that under conditions of… (More)
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Highly Cited
2006
Highly Cited
2006
Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
CD44 is a multifunctional protein involved in cell adhesion and signaling. The role of CD44 in prostate cancer (PCa) development… (More)
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Highly Cited
2006
Highly Cited
2006
The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation.
BACKGROUND If cancer arises and is maintained by a small population of cancer-initiating cells within every tumor, understanding… (More)
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Highly Cited
2006
Highly Cited
2006
Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
Recently, a small population of cancer stem cells in adult and pediatric brain tumors has been identified. Some evidence has… (More)
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Highly Cited
2000
Highly Cited
2000
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis.
We have uncovered a novel functional relationship between the hyaluronan receptor CD44, the matrix metalloproteinase-9 (MMP-9… (More)
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Highly Cited
1999
Highly Cited
1999
LYVE-1, a New Homologue of the CD44 Glycoprotein, Is a Lymph-specific Receptor for Hyaluronan
The extracellular matrix glycosaminoglycan hyaluronan (HA) is an abundant component of skin and mesenchymal tissues where it… (More)
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Highly Cited
1994
Highly Cited
1994
ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletons
The ERM family members, ezrin, radixin, and moesin, localizing just beneath the plasma membranes, are thought to be involved in… (More)
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Highly Cited
1990
Highly Cited
1990
CD44 is the principal cell surface receptor for hyaluronate.
CD44 is a broadly distributed cell surface protein thought to mediate cell attachment to extracelular matrix components or… (More)
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