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CCND1 protein, human
Known as:
PRAD1 oncogene protein, human
, D11S287E
, BCL-1 oncogene protein, human
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G1/S-specific cyclin-D1 (295 aa, ~34 kDa) is encoded by the human CCND1 gene. This protein is involved in the regulation of the G1/S transition of…
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National Institutes of Health
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Related topics
Related topics
16 relations
BCL1
BTG Cell Cycle Regulation Pathway
Beta-Catenin Accumulation Pathway
CCND1 gene
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Broader (1)
Cyclin D1
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Evaluation of CCND1 amplification and CyclinD1 expression: diffuse and strong staining of CyclinD1 could have same predictive roles as CCND1 amplification in ER positive breast cancers.
Zhishuang Li
,
Jingjing Cui
,
Qiong Yu
,
Xiaojuan Wu
,
Aifeng Pan
,
Li Li
American journal of translational research
2016
Corpus ID: 40519717
CCND1 is amplified in around 10-20% of primary breast cancers and preferentially occurs in ER positive tumors. Though CCND1…
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Highly Cited
2014
Highly Cited
2014
Dihydroartemisinin inhibits cell proliferation via AKT/GSK3β/cyclinD1 pathway and induces apoptosis in A549 lung cancer cells.
K. Liao
,
Juan Li
,
Zhilin Wang
International Journal of Clinical and…
2014
Corpus ID: 9612363
Lung cancer is the most common cause of cancer-related death in the world. The main types of lung cancer are small cell lung…
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Highly Cited
2014
Highly Cited
2014
Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease
V. Medici
,
N. Shibata
,
+7 authors
J. LaSalle
Epigenetics
2014
Corpus ID: 207515149
Maternal diet can affect fetal gene expression through epigenetic mechanisms. Wilson disease (WD), which is caused by autosomal…
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Highly Cited
2011
Highly Cited
2011
CCND1 as a Predictive Biomarker of Neoadjuvant Chemotherapy in Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma
Zhien Feng
,
W. Guo
,
+16 authors
Wantao Chen
PLoS ONE
2011
Corpus ID: 17281158
Background Cyclin D1 (CCND1) has been associated with chemotherapy resistance and poor prognosis. In this study, we tested the…
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Review
2005
Review
2005
External Imaging of CCND1, MYC, and KRAS Oncogene mRNAs with Tumor‐Targeted Radionuclide‐PNA‐Peptide Chimeras
X. Tian
,
A. Chakrabarti
,
+8 authors
E. Wickstrom
Annals of the New York Academy of Sciences
2005
Corpus ID: 23287951
Abstract: In 2005, breast cancer will kill approximately 40,410 women in the U.S., and pancreatic cancer will kill approximately…
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Highly Cited
2003
Highly Cited
2003
Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma
J. Molenaar
,
P. V. van Sluis
,
K. Boon
,
R. Versteeg
,
H. Caron
Genes, Chromosomes and Cancer
2003
Corpus ID: 21285780
Cyclin D1 regulates G1 cell cycle progression by controlling the phosphorylation of the retinoblastoma protein. This pathway is…
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Highly Cited
2000
Highly Cited
2000
Characterization of the Minimal Replicon of a Cryptic Deinococcus radiodurans SARK Plasmid and Development of Versatile Escherichia coli-D. radiodurans Shuttle Vectors
Rob Meima
,
M. Lidstrom
Applied and Environmental Microbiology
2000
Corpus ID: 34067808
ABSTRACT The nucleotide sequence of a 12-kb fragment of the crypticDeinococcus radiodurans SARK plasmid pUE10 was determined, in…
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Highly Cited
1995
Highly Cited
1995
Abnormalities in the PRAD1 (CYCLIN D1 / BCL‐1) oncogene are frequent in cervical and vulvar squamous cell carcinoma cell lines
R. Kurzrock
,
S. Ku
,
M. Talpaz
Cancer
1995
Corpus ID: 24010716
Background. CYCLIN D1, a cell‐cycle control gene, recently has been shown to be identical to an oncogene alternatively known as…
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Highly Cited
1993
Highly Cited
1993
PRAD1/lCyclin D1 proto‐oncogene: Genomic organization, 5′ dna sequence, and sequence of a tumor‐specific rearrangement breakpoint
T. Motokura
,
A. Arnold
1993
Corpus ID: 32254958
PRAD1 (previously D11S287) is a putative proto‐oncogene at 11q13, activated by overexpression through gene rearrangement or gene…
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Highly Cited
1991
Highly Cited
1991
Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors.
Rosenberg Cl
,
Kim Hg
,
T. Shows
,
H. Kronenberg
,
A. Arnold
Oncogene
1991
Corpus ID: 42296429
We report the detailed molecular characterization of a human parathyroid adenoma with a clonal parathyroid hormone gene…
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