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A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome.
TLDR
It is proposed that KvDMR1 and/or its associated antisense RNA (KvLQT1-AS) represents an additional imprinting control element or center in the human 11p15.5 and mouse distal 7 imprinted domains.
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A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization
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NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia.
TLDR
The possibility that NUP98 may be a previously unsuspected target for chromosomal translocations in patients with t-AML is raised.
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cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines
The amino-acid sequence of the precursor of the human tumour cell line-derived platelet-derived growth factor (PDGF) A-chain has been deduced from complementary DNA clones and the gene localized to…
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Identification of a new endothelial cell growth factor receptor tyrosine kinase.
TLDR
A new growth factor receptor tyrosine kinase (RTK) gene (designated KDR) has been cloned from a human endothelial cell cDNA library, and is expressed as a 7.0 kb transcript and localized to human chromosome 4.
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tyk2, prototype of a novel class of non-receptor tyrosine kinase genes.
TLDR
It is proposed that tyk2 is the prototype of a new class of non-receptor protein tyrosine kinases that is widely expressed in hematopoietic and non-hematopoetic cell lines and mapped to chromosome 19p13.2.
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Brn-3b: a POU domain gene expressed in a subset of retinal ganglion cells
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Cloning of human lysyl hydroxylase: complete cDNA-derived amino acid sequence and assignment of the gene (PLOD) to chromosome 1p36.3----p36.2.
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Human facilitative glucose transporters. Isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose…
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Cloning of human and mouse EBI1, a lymphoid-specific G-protein-coupled receptor encoded on human chromosome 17q12-q21.2.
TLDR
It is determined that this receptor, also reported as the Epstein-Barr-induced cDNA EBI1, is expressed in normal lymphoid tissues and in several B- and T-lymphocyte cell lines, and its sequence and gene structure suggest that it is related to the receptors that recognize chemoattractants.
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