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Inflammation is triggered when innate immune cells detect infection or tissue injury. Surveillance mechanisms involve pattern… Expand Mammalian cells respond to endoplasmic reticulum (ER) stress by attenuation of protein translation mediated through the PERK-eIF2… Expand The onset of allergic inflammation in the lung is driven by a complex genetic program. This study shows that found in… Expand BACKGROUND
Cancer chemopreventive agents transcriptionally induce genes whose protein products can protect cells from chemical… Expand The IL-18 binding protein (IL-18BP) is a circulating inhibitor of the proinflammatory cytokine IL-18. It is constitutively… Expand Two members of the C/EBP family of basic region‐leucine zipper proteins enriched in the liver, C/EBP (C/EBP alpha) and CRP2 (C… Expand We report on the identification of a nuclear protein that serves as a dominant-negative inhibitor of the transcription factors C… Expand We report the isolation and characterization of cDNA clones that encode a protein with the same DNA binding specificity as the… Expand The transcription factor C/EBP uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of… Expand C/EBP is a rat liver nuclear protein capable of sequence-specific interaction with DNA. The DNA sequences to which C/EBP binds in… Expand