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CASP4 gene

Known as: Caspase 4, Apoptosis-Related Cysteine Protease Gene, TX, ICH2 
This gene is involved in the promotion of apoptosis.
National Institutes of Health

Related topics

Related topics

5 relations
ApoptosisCASP4 protein, humanHydrolysisProteolysis

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CASP4 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
A further leap of improvement in tertiary structure prediction in CASP13 prompts new routes for future assessments
We present our assessment of tertiary structure predictions for hard targets in Critical Assessment of Structure Prediction round… 
Highly Cited
2019
Highly Cited
2019
Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Inflammasome
Highly Cited
2016
Highly Cited
2016
Improved de novo structure prediction in CASP11 by incorporating coevolution information into Rosetta
We describe CASP11 de novo blind structure predictions made using the Rosetta structure prediction methodology with both… 
Highly Cited
2016
Highly Cited
2016
New encouraging developments in contact prediction: Assessment of the CASP11 results
This article provides a report on the state‐of‐the‐art in the prediction of intra‐molecular residue‐residue contacts in proteins… 
Highly Cited
2015
Highly Cited
2015
Large-scale determination of previously unsolved protein structures using evolutionary information
The prediction of the structures of proteins without detectable sequence similarity to any protein of known structure remains an… 
Highly Cited
2013
Highly Cited
2013
Transmembrane Protein 214 (TMEM214) Mediates Endoplasmic Reticulum Stress-induced Caspase 4 Enzyme Activation and Apoptosis*
Background: ER stress induces apoptosis. Results: TMEM214 is localized at the ER and is required for ER stress-induced caspase 4… 
Highly Cited
2008
Highly Cited
2008
OSU-03012 Stimulates PKR-Like Endoplasmic Reticulum-Dependent Increases in 70-kDa Heat Shock Protein Expression, Attenuating Its Lethal Actions in Transformed Cells
We have further defined mechanism(s) by which 2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl… 
Highly Cited
2006
Highly Cited
2006
Specific killing of multiple myeloma cells by (-)-epigallocatechin-3-gallate extracted from green tea: biologic activity and therapeutic implications.
Epigallocatechin-3-gallate (EGCG), a polyphenol extracted from green tea, is an antioxidant with chemopreventive and… 
Highly Cited
2002
Highly Cited
2002
Gene Expression Profiling in Chronic Myeloid Leukemia Patients Treated with Hydroxyurea
Using array technology that allows the simultaneous detection of gene expression of hundreds of genes, four patients with chronic… 
Highly Cited
2001
Highly Cited
2001
Comparative modeling of CASP4 target proteins: Combining results of sequence search with three‐dimensional structure assessment
Comparative modeling aims at constructing molecular models for proteins of unknown structure, by using known structures of… 
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