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Modern Molecular Photochemistry
- N. Turro
- 1 August 1978
During the last two decades the photochemistry of organic molecules has grown into an important and pervasive branch of organic chemistry. In "Modern Molecular Photochemistry", the author brings…
The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging.
Data suggest that in LC neurons, the iron mobilization and toxicity is lower than that in SN and is efficiently buffered by NM, which may explain at least one of the reasons underlying lower vulnerability of LC compared to SN in Parkinsonian syndromes.
Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles.
- D. Sulzer, J. Bogulavsky, L. Zecca
- Biology, ChemistryProceedings of the National Academy of Sciences…
- 24 October 2000
NM induced in rat substantia nigra and PC12 cell cultures by exposure to l-dihydroxyphenylalanine, which is rapidly converted to dopamine in the cytosol, and NM synthesis was inhibited by the iron chelator desferrioxamine, indicating that cytosolic DA and dihydroxymelanin are oxidized by iron-mediated catalysis to membrane-impermeant quinones and semiquinones.
Modern Molecular Photochemistry of Organic Molecules
1. Molecular Photochemistry of Organic Compounds: An Overview 2. Electronic, Vibrational, and Spin Configurations of Electronically Excited States 3. Transitions between States: Photophysical…
Mixed-ligand complexes of ruthenium(II): factors governing binding to DNA
Photoinitiated Polymerization: Advances, Challenges, and Opportunities
The use of photoinitiated polymerization is continuously growing in industry as reflected by the large number of applications in not only conventional areas such as coatings, inks, and adhesives but…
Photosensitization by reversible electron transfer: theories, experimental evidence, and examples
Principles of Molecular Photochemistry: An Introduction
Preface Molecular Photochemistry of Organic Compounds: An Overview Electronic, Vibrational, and Spin Configurations of Electronically Excited States Transitions Between States: Photophysical…
Formation of a nonaoxirane from A2E, a lipofuscin fluorophore related to macular degeneration, and evidence of singlet oxygen involvement.
- S. Ben-Shabat, Y. Itagaki, S. Jockusch, J. Sparrow, N. Turro, K. Nakanishi
- ChemistryAngewandte Chemie
- 1 March 2002
The ability of A2E to serve as an initiator of photodamage may be relevant to studies linking the incidence of advanced atrophic AMD with blue light exposure, particularly in later life.
New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals
- L. Zecca, C. Bellei, F. Zucca
- Biology, ChemistryProceedings of the National Academy of Sciences
- 11 November 2008
The synthesis of neuromelanins in the various regions of the human brain is an important protective process because the melanic component is generated through the removal of reactive/toxic quinones that would otherwise cause neurotoxicity.