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Bax protein

Known as: BAX Isoform Alpha, bcl 2 Associated X Protein, BCL2-Associated X Protein 
A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS… 
National Institutes of Health

Related topics

Related topics

24 relations
ApoptosisApoptosis PromoterBAX geneBH1 Domain

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell.
Highly Cited
2008
Highly Cited
2008
Bax Inhibitor-1 Is a pH-dependent Regulator of Ca2+ Channel Activity in the Endoplasmic Reticulum*
In this study, Bax inhibitor-1 (BI-1) overexpression reduces the ER pool of Ca2+ released by thapsigargin. Cells overexpressing… 
Highly Cited
2004
Highly Cited
2004
Bax Mediates the Apoptosis-Sensitizing Effect of Maspin
Maspin, a serine protease inhibitor (serpin), can suppress tumor growth and metastasis in vivo and tumor cell motility and… 
Highly Cited
2004
Highly Cited
2004
beta-Carotene exacerbates DNA oxidative damage and modifies p53-related pathways of cell proliferation and apoptosis in cultured cells exposed to tobacco smoke condensate.
Human intervention trials have suggested that supplemental beta-carotene resulted in more cancer in smokers, whereas it was… 
Highly Cited
2004
Highly Cited
2004
Fatal liaisons of p53 with Bax and Bak
p53 can induce apoptosis through its well defined role as a regulator of transcription, but also by a less well defined… 
Review
2003
Review
2003
Mitochondrial membrane permeabilisation by Bax/Bak.
Highly Cited
2002
Highly Cited
2002
Glutathione Levels and BAX Activation during Apoptosis Due to Oxidative Stress in Cells Expressing Wild-type and Mutant Cystic Fibrosis Transmembrane Conductance Regulator*
Cystic fibrosis is characterized by chronic inflammation and an imbalance in the concentrations of alveolar and lung oxidants and… 
Highly Cited
2001
Highly Cited
2001
Bcl-XL–Caspase-9 Interactions in the Developing Nervous System: Evidence for Multiple Death Pathways
Programmed cell death is critical for normal nervous system development and is regulated by Bcl-2 and Caspase family members… 
Highly Cited
2000
Highly Cited
2000
Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals
Drug resistance remains a serious limiting factor in the treatment of acute myeloid leukaemia (AML) either at initial… 
Highly Cited
2000
Highly Cited
2000
Translocation of Bax to mitochondria induces apoptotic cell death in Indole-3-carbinol (I3C) treated breast cancer cells
Epidemiological studies have suggested that the consumption of fruits and vegetables that provide several classes of compounds… 
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