Bax protein

Known as: BAX Isoform Alpha, bcl 2 Associated X Protein, BCL2-Associated X Protein 
A member of the Bcl-2 protein family and homologous partner of C-BCL-2 PROTO-ONCOGENE PROTEIN. It regulates the release of CYTOCHROME C and APOPTOSIS… (More)
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
A central issue in the regulation of apoptosis by the Bcl-2 family is whether its BH3-only members initiate apoptosis by directly… (More)
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Highly Cited
2005
Highly Cited
2005
Using a Bax-dependent membrane-permeabilization assay, we show that peptides corresponding to the BH3 domains of Bcl-2 family… (More)
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Highly Cited
2003
Highly Cited
2003
The c-Jun NH(2)-terminal kinase (JNK) is activated when cells are exposed to environmental stress, including UV radiation. Gene… (More)
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Highly Cited
1999
Highly Cited
1999
Here we report that in staurosporine-induced apoptosis of HeLa cells, Bid, a BH3 domain containing protein, translocates from the… (More)
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Highly Cited
1998
Highly Cited
1998
Bax is a pro-apoptotic member of the Bcl-2 protein family that resides in the outer mitochondrial membrane. It is controversial… (More)
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Highly Cited
1998
Highly Cited
1998
Cytochrome c release and the mitochondrial permeability transition (PT), including loss of the transmembrane potential (Deltapsi… (More)
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Highly Cited
1998
Highly Cited
1998
Expression of the pro-apoptotic molecule BAX has been shown to induce cell death. While BAX forms both homo- and heterodimers… (More)
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Highly Cited
1997
Highly Cited
1997
Bax, a member of the Bcl-2 protein family, accelerates apoptosis by an unknown mechanism. Bax has been recently reported to be an… (More)
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Highly Cited
1995
Highly Cited
1995
To extend the mammalian cell death pathway, we screened for further Bcl-2 interacting proteins. Both yeast two-hybrid screening… (More)
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Highly Cited
1993
Highly Cited
1993
Bcl-2 protein is able to repress a number of apoptotic death programs. To investigate the mechanism of Bcl-2's effect, we… (More)
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