BAX gene

Known as: BAX, BCL2-Associated X Protein Gene, BCL2-associated X protein 
This gene is involved in the regulation of apoptosis by binding p53 protein, which accelerates this mechanism of cell death.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
051019942017

Papers overview

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2005
2005
Multiple apoptotic stimuli induce conformational changes in Bax, a proapoptotic protein from the Bcl-2 family and its deficiency… (More)
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2002
2002
Both the human and the mouse bax promoters contain p53 binding sites which are sufficient to confer p53-dependent transcriptional… (More)
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2001
2001
The mechanism of cell death induced by West Nile virus (WNV), a causative agent of human febrile syndrome and encephalitis, was… (More)
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2000
2000
The bax gene plays a critical role in signaling apoptosis and expression through gene transfer may be valuable in the treatment… (More)
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Highly Cited
1999
Highly Cited
1999
Oxygen radicals are important components of metazoan apoptosis. We have found that apoptosis can be induced in the yeast… (More)
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Highly Cited
1999
Highly Cited
1999
Several human inhibitor of apoptosis (IAP) family proteins function by directly inhibiting specific caspases in a mechanism that… (More)
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1999
1999
The influence of bcl-2 and bax expression on apoptotic cell death in mouse intestinal epithelia was assessed using homozygously… (More)
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1998
1998
BACKGROUND bcl-2 and bax belong to the bcl-2-related gene family, which marks a new class of genes that influence apoptosis. The… (More)
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Highly Cited
1995
Highly Cited
1995
The loss of ovarian follicles through atresia, which accounts for greater than 99% of postnatal female germ cell depletion, is… (More)
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Highly Cited
1994
Highly Cited
1994
The protein encoded by the bcl-2 gene is a regulator of programmed cell death and apoptosis. The cell survival-promoting activity… (More)
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