BH1 Domain

Known as: BCL-2 Homology 1 Domain 
Found in proteins that regulate apoptosis, conserved a-helix BCL-2 Homology (BH1-4) Domains are critical to protein apoptotic function and the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2016
01219962016

Papers overview

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2016
2016
The antiapoptotic protein BCL2 is overexpressed in several cancers and contributes to prolonged cell survival and chemoresistance… (More)
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2014
2014
Mcl-1 is a member of the Bcl-2 family protein; its degradation is required for the initiation of apoptosis. The mechanism… (More)
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2005
2005
Although Puma (p53 upregulated modulator of apoptosis) was known as a principal mediator of cell death in response to diverse… (More)
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2004
2004
Studies of CD95 (APO-1/Fas), a member of the death receptor family, have revealed that it is involved in two primary CD95… (More)
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2003
2003
To investigate the exact biochemical functions by which Bcl-2 regulates apoptosis, we established a stable human small cell lung… (More)
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2003
2003
Apoptosis or programmed cell death plays an important role in a wide variety of physiologic processes and is regulated by… (More)
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2000
2000
 The murine gammaherpesvirus (MHV-68) M11 gene encodes a protein with BH1 domain homology to Bcl-2. We found that the M11 gene… (More)
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1999
1999
Certain Bcl-2 family members promote cell survival, whereas others promote apoptosis. To explore further how heterodimerization… (More)
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1997
1997
The function of the African swine fever virus (ASFV) bcl-2 homologue, gene A179L, in the regulation of apoptosis was investigated… (More)
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Highly Cited
1996
Highly Cited
1996
The BCL-2 family of proteins consists of both antagonists (e.g., BCL-2) and agonists (e.g., BAX) that regulate apoptosis and… (More)
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