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BH1 Domain

Known as: BCL-2 Homology 1 Domain 
Found in proteins that regulate apoptosis, conserved a-helix BCL-2 Homology (BH1-4) Domains are critical to protein apoptotic function and the… 
National Institutes of Health

Related topics

Related topics

6 relations
BCL-XL ProteinBCL2L10 protein, humanBax proteinBcl-2-Related Ovarian Killer Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Novel BCL2 inhibitor, Disarib induces apoptosis by disruption of BCL2‐BAK interaction
2016
2016
Identification of a novel BCL2‐specific inhibitor that binds predominantly to the BH1 domain
The antiapoptotic protein BCL2 is overexpressed in several cancers and contributes to prolonged cell survival and chemoresistance… 
2015
2015
Determination of groundwater-surface water interaction, upper Berg River catchment, South Africa
2014
2014
The VTLISFG motif in the BH1 domain plays a significant role in regulating the degradation of Mcl-1☆
2012
2012
Abstract 2017: Galectin-3 SNP rs10148371 in the anti-death motif NWGR is related to the colon cancer incidence in African Americans
Survival after cancer diagnosis is poorer for African Americans than for Caucasians. While some of this survival difference is… 
Highly Cited
2004
Highly Cited
2004
Endogenous Galectin-3 Determines the Routing of CD95 Apoptotic Signaling Pathways
Studies of CD95 (APO-1/Fas), a member of the death receptor family, have revealed that it is involved in two primary CD95… 
2003
2003
Deletion of the BH1 Domain of Bcl-2 Accelerates Apoptosis by Acting in a Dominant Negative Fashion*
To investigate the exact biochemical functions by which Bcl-2 regulates apoptosis, we established a stable human small cell lung… 
2003
2003
A novel strategy using single-chain antibody to show the importance of Bcl-2 in mast cell survival.
Apoptosis or programmed cell death plays an important role in a wide variety of physiologic processes and is regulated by… 
Highly Cited
1999
Highly Cited
1999
Survival activity of Bcl-2 homologs Bcl-w and A1 only partially correlates with their ability to bind pro-apoptotic family members
Certain Bcl-2 family members promote cell survival, whereas others promote apoptosis. To explore further how heterodimerization… 
Highly Cited
1997
Highly Cited
1997
Inhibition of apoptosis by the African swine fever virus Bcl-2 homologue: role of the BH1 domain.
The function of the African swine fever virus (ASFV) bcl-2 homologue, gene A179L, in the regulation of apoptosis was investigated… 
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