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BMY 25282

Known as: BMY-25282 
National Institutes of Health

Papers overview

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1993
1993
Contrasting molecular cytotoxic mechanisms of mitomycin C and its two analogs, BMY 25282 and BMY 25067, in isolated rat hepatocytes.
1991
1991
Additional nucleotide derivatives of mitosenes. Synthesis and activity against parental and multidrug resistant L1210 leukemia.
Cytidine 5'-monophosphate and 5'-ara-CMP conjugates of 2,7-diaminomitosene, with the phosphate groups linked to C-1, were… 
1989
1989
Free-radical formation by mitomycin C and its novel analogs in cardiac microsomes and the perfused rat heart.
1989
1989
Modification of the metabolism and cytotoxicity of bioreductive alkylating agents by dicoumarol in aerobic and hypoxic murine tumor cells.
We have demonstrated previously that dicoumarol (DIC) increased the generation of reactive metabolites from mitomycin C (MC) in… 
1989
1989
Effect of the superoxide dismutase inhibitor, diethyldithiocarbamate, on the cytotoxicity of mitomycin antibiotics.
Mitomycin C (MC) and its structural analogs porfiromycin (PM), BMY-25282 and BL-6783 are toxic to EMT6 cells under aerobic and… 
1989
1989
Cardiac, renal, and pulmonary toxicity of several mitomycin derivatives in rats.
The potential cardiotoxicity, nephrotoxicity, and pulmonary toxicity of several mitomycin (MMC) derivatives, BMY-25067 (N-7-[2-(4… 
1988
1988
Conformations of complexes between mitomycins and decanucleotides. 3. Sequence specificity, binding at C-10, and mitomycin analogues.
Molecular mechanics simulation of the interactions of mitomycin C and certain analogues with DNA models are presented. The… 
1985
1985
Effects of BMY 25282, a mitomycin C analogue, in mitomycin C-resistant human colon cancer cells.
BMY 25282, a newly designed analogue of mitomycin C (MMC), was assessed for its non-cross-resistant cytotoxic and biochemical… 
Highly Cited
1985
Highly Cited
1985
Chemotherapeutic attack of hypoxic tumor cells by the bioreductive alkylating agent mitomycin C.
1985
1985
Antitumor activity and toxicity in animals of BMY-25282, a new mitomycin derivative.
BMY-25282, 7-N-(dimethylamino methylene)mitomycin C, is one of a novel series of amidino mitomycin derivatives. Some of these… 
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