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Azathioprine

Known as: 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine, 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine, Azathioprine [Chemical/Ingredient] 
A purine analogue with cytotoxic and immunosuppressive activity. Azathioprine is a prodrug that is converted by hepatic xanthine oxidase to its… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Our objective was to update the EULAR recommendations for the management of systemic lupus erythematosus (SLE), based on emerging… Expand
Review
2018
Review
2018
Unrestricted cell proliferation is a hallmark of cancer. Purines are basic components of nucleotides in cell proliferation, thus… Expand
Review
2018
Review
2018
  • J. Schmidt
  • Journal of neuromuscular diseases
  • 2018
  • Corpus ID: 46926504
Inflammatory disorders of the skeletal muscle include polymyositis (PM), dermatomyositis (DM), (immune mediated) necrotizing… Expand
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Review
2018
Review
2018
Neuromyelitis optica spectrum disorders (NMOSD) are autoantibody mediated chronic inflammatory diseases. Serum antibodies (Abs… Expand
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Review
2018
Review
2018
Behçet’s syndrome (BS) is a complex vasculitis, characterised by peculiar histological, pathogenetic and clinical features… Expand
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Review
2016
Review
2016
AbstractTo review the reported evidence on the therapeutic management of IgG4-related disease (IgG4-RD) in clinical practice.A… Expand
Highly Cited
2012
Highly Cited
2012
BACKGROUND A combination of prednisone, azathioprine, and N-acetylcysteine (NAC) has been widely used as a treatment for… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease… Expand
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Highly Cited
2003
Highly Cited
2003
Azathioprine and its metabolite 6-mercaptopurine (6-MP) are immunosuppressive drugs that are used in organ transplantation and… Expand
Review
2002
Review
2002
Chemotherapeutics are the most effective treatment for metastatic tumours. However, the ability of cancer cells to become… Expand
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