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Azathioprine

Known as: 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine, 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine, Azathioprine [Chemical/Ingredient] 
A purine analogue with cytotoxic and immunosuppressive activity. Azathioprine is a prodrug that is converted by hepatic xanthine oxidase to its… 
National Institutes of Health

Related topics

Related topics

33 relations

Broader (5)

AntimetabolitesAntimetabolites, AntineoplasticAntirheumatic AgentsImmunosuppressive Agents
Azathioprine 50 MG Oral Tablet [Imuran]Azathioprine:MCnc:Pt:Ser/Plas:QnAzathioprine:PrThr:Pt:Ser/Plas:OrdCrohn Disease

Narrower (3)

ImuranImurelthiamiprine

Papers overview

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2012
2012
Strategy of directly employing paclitaxel to construct vesicles.
A class of aza-arm modified β-cyclodextrins were found to be able to trap paclitaxel (PTX), an effective but strongly hydrophobic… 
2001
2001
Thiadiazole-derived expanded heteroazaporphyrinoids.
[structure: see text] Heteroannulenes 1 and 3 containing three subunits of isoindole or pyrrole, respectively, three 1,3,4… 
Highly Cited
1998
Highly Cited
1998
Long-term outcome of a prospective randomized trial of conversion from cyclosporine to azathioprine treatment one year after renal transplantation.
BACKGROUND Since the introduction of cyclosporine (CsA), 1-year renal allograft survival has improved, but concern persists about… 
1992
1992
Molecular yardsticks. Rigid probes to define the spatial dimensions of the benzodiazepine receptor binding site.
A series of rigid planar azadiindoles (8a, 8b, and 8d), benzannelated pyridodiindoles (11a, 11b, and 11d), and… 
1985
1985
2-[(4-Azido-2-nitrophenyl)amino]ethyl triphosphate, a novel chromophoric and photoaffinity analogue of ATP. Synthesis, characterization, and interaction with myosin subfragment 1.
A facile and high-yield synthesis of a new ATP analogue, 2-[(4-azido-2-nitrophenyl)amino]ethyl triphosphate (NANTP), is described… 
Highly Cited
1982
Highly Cited
1982
Photophysical and photochemical behaviour of stilbene-like molecules and their aza-analogues
Abstract 
Review
1981
Review
1981
Azathioprine teratogenicity: review of the literature and case report.
: An infant born with preaxial polydactyly to a mother taking azathioprine throughout pregnancy is described. Experimental… 
1977
1977
Separation of aza-arenes by high-pressure liquid chromatography.
Fast, efficient liquid chromatographic separations of aza-arenes were obtained using both, reversed-phase, and adsorbent packings… 
Highly Cited
1976
Highly Cited
1976
Gastrointestinal candidiasis in rats treated with antibiotics, cortisone, and azathioprine
Conventional albino rats treated with peroral chloramphenicol, gentamicin, and/or parenteral cortisone were challenged with… 
Highly Cited
1975
Highly Cited
1975
Erythroid Toxicity of Azathioprine
In a population of 70 stable renal allograft recipients receiving azathioprine, macrocytosis was present in a majority and its…