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Azathioprine

Known as: 6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine, 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine, Azathioprine [Chemical/Ingredient] 
A purine analogue with cytotoxic and immunosuppressive activity. Azathioprine is a prodrug that is converted by hepatic xanthine oxidase to its… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Checkpoint inhibitors (CPIs) have dramatically increased survival in patients with certain types of cancer (1). To date, 6 CPIs… Expand
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Review
2017
Review
2017
BACKGROUND Mucosal healing is an important therapeutic endpoint in the management of Crohn's disease (CD) and ulcerative colitis… Expand
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Review
2017
Review
2017
  • Hazel H. Szeto
  • Journal of the American Society of Nephrology…
  • 2017
  • Corpus ID: 13696591
AKI is associated with high morbidity and mortality, and it predisposes to the development and progression of CKD. Novel… Expand
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Review
2017
Review
2017
DNA methylation aberrancies are hallmarks of human cancers and are characterized by global DNA hypomethylation of repetitive… Expand
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Review
2017
Review
2017
Various therapeutic advances have led to a paradigm shift in the clinical management of patients with IBD. The introduction of… Expand
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Review
2016
Review
2016
A European League Against Rheumatism (EULAR) task force was established to define points to consider on use of antirheumatic… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND The combination of cyclophosphamide and glucocorticoids leads to remission in most patients with antineutrophil… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Current standard therapy for Wegener's granulomatosis and microscopic polyangiitis combines corticosteroids and… Expand
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Review
2002
Review
2002
Chemotherapeutics are the most effective treatment for metastatic tumours. However, the ability of cancer cells to become… Expand
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