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Aurora Kinase A

Known as: Aurora A, AuroraA Kinase, Serine/Threonine-Protein Kinase 15 
An aurora kinase that localizes to the CENTROSOME during MITOSIS and is involved in centrosome regulation and formation of the MITOTIC SPINDLE… 
National Institutes of Health

Related topics

Related topics

39 relations
AURKA geneAURKA wt AlleleAurora A Kinase Inhibitor TAS-119Aurora Kinase Inhibitor

Narrower (3)

Aurka protein, mouseAurka protein, rataur protein, Drosophila

Papers overview

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2013
2013
Assessment of Aurora a Kinase Expression in Breast Cancer: A Tool for Early Diagnosis?
Aurora A kinase is overexpressed in many cancers but the status of this protein in the breast cancer often varies. We investigate… 
2013
2013
Differential expression of aurora-A kinase in T-cell lymphomas
Aurora-A is a mitotic kinase implicated in oncogenesis and is known to be overexpressed in B-cell lymphomas and plasma cell… 
2010
2010
Using cross-dating techniques to validate ages of aurora rockfish (Sebastes aurora): estimates of age, growth and female maturity
Since fishery management regulations have shifted much of the groundfish trawl effort in the northeastern Pacific from the… 
2010
2010
Regulation of Aurora B Kinase by the Lipid Raft Protein Flotillin-1*
The lipid raft protein Flotillin-1 was previously shown to be required for cell proliferation. Here we show that it is critical… 
2009
2009
Aurora A regulates prometaphase progression by inhibiting the ability of RASSF1A to suppress APC-Cdc20 activity.
The Aurora (Ipl) kinase family plays important roles in the regulation of mitosis and tumorigenesis. The tumor suppressor RASSF1A… 
2009
2009
Stable knockdown of Aurora-A by vector-based RNA interference in human esophageal squamous cell carcinoma cell line inhibits tumor cell proliferation, invasion and enhances apoptosis
Esophageal squamous cell carcinoma (ESCC) is one of the most malignant cancers, and the existing treatment approaches have not… 
2007
2007
Aurora-A kinase interacting protein 1 (AURKAIP1) promotes Aurora-A degradation through an alternative ubiquitin-independent pathway.
Mitotic Aurora-A is an oncogene, which undergoes a cell-cycle-dependent regulation of both its synthesis and degradation… 
Highly Cited
2004
Highly Cited
2004
Aberrant quantity and localization of Aurora-B/AIM-1 and survivin during megakaryocyte polyploidization and the consequences of Aurora-B/AIM-1-deregulated expression.
Megakaryocytes skip late anaphase and cytokinesis during endomitosis. We found normal expression and localization of a… 
Highly Cited
2004
Highly Cited
2004
STK15/Aurora‐A expression in primary breast tumors is correlated with nuclear grade but not with prognosis
DNA amplification on chromosome 20q13 is commonly detected in breast carcinoma and is correlated with poor prognosis. STK15 maps… 
1997
1997
Assignment of STK6 to human chromosome 20q13.2-->q13.3 and a pseudogene STK6P to 1q41-->q42.
Fluorescence in situ hybridization analysis of human STK6 encoding a mitotic centrosomal protein kinase, Aik, revealed two… 
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