Aurora Kinase A

Known as: Aurora A, AuroraA Kinase, Serine/Threonine-Protein Kinase 15 
An aurora kinase that localizes to the CENTROSOME during MITOSIS and is involved in centrosome regulation and formation of the MITOTIC SPINDLE… (More)

Topic mentions per year

Topic mentions per year

2000-2018
05010015020002018

Papers overview

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Review
2015
Review
2015
The Aurora kinase family of kinases (Aurora A, B, and C) are involved in multiple mitotic events, and aberrant expression of… (More)
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Highly Cited
2008
Highly Cited
2008
A central question in the study of cell proliferation is, what controls cell-cycle transitions? Although the accumulation of… (More)
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Highly Cited
2008
Highly Cited
2008
Polo-like kinase-1 (PLK1) is an essential mitotic kinase regulating multiple aspects of the cell division process. Activation of… (More)
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Highly Cited
2007
Highly Cited
2007
Increased Aurora A expression occurs in a variety of human cancers and induces chromosomal abnormalities during mitosis… (More)
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Highly Cited
2003
Highly Cited
2003
The Aurora/Ipl1 family of protein kinases plays multiple roles in mitosis and cytokinesis. Here, we describe ZM447439, a novel… (More)
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Highly Cited
2003
Highly Cited
2003
Aurora-A, a member of the Aurora/Ipl1-related kinase family, is overexpressed in various types of cancer and considered to play… (More)
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Highly Cited
2003
Highly Cited
2003
The activated form of Ran (Ran-GTP) stimulates spindle assembly in Xenopus laevis egg extracts, presumably by releasing spindle… (More)
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Highly Cited
2003
Highly Cited
2003
The serine-threonine kinase gene AURORA-A is commonly amplified in epithelial malignancies. Here we show that elevated Aurora-A… (More)
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Highly Cited
2002
Highly Cited
2002
Aurora-A is a serine-threonine kinase implicated in the assembly and maintenance of the mitotic spindle. Here we show that human… (More)
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Highly Cited
2001
Highly Cited
2001
Centrosomes mature as cells enter mitosis, accumulating gamma-tubulin and other pericentriolar material (PCM) components. This… (More)
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