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AURKA wt Allele

Known as: AIK, AURA, Aurora Kinase A wt Allele 
Human AURKA wild-type allele is located within 20q13.2-13.3 and is approximately 23 kb in length. This allele, which encodes serine/threonine-protein… 
National Institutes of Health

Related topics

Related topics

10 relations
20q13.2-q13.3Aurora Kinase ACell Cycle ControlCytoskeletal Modeling

Broader (1)

AURKA gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Prevalence and size of directly detected patent foramen ovale in migraine with aura
Background: Transcranial contrast Doppler studies have shown an increased prevalence of right-to-left shunts in patients with… 
Highly Cited
2005
Highly Cited
2005
Aurora A Kinase-Coated Beads Function as Microtubule-Organizing Centers and Enhance RanGTP-Induced Spindle Assembly
Highly Cited
2000
Highly Cited
2000
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation
Aurora2 is a cell cycle regulated serine/threonine protein kinase which is overexpressed in many tumor cell lines. We demonstrate… 
Highly Cited
1999
Highly Cited
1999
Centrosomal kinase AIK1 is overexpressed in invasive ductal carcinoma of the breast.
A centrosomal serine/threonine kinase, AIK1(3)/breast tumor amplified kinase/aurora2, which was recently identified as an… 
Highly Cited
1997
Highly Cited
1997
Cell Cycle-dependent Expression and Spindle Pole Localization of a Novel Human Protein Kinase, Aik, Related to Aurora of Drosophila and Yeast Ipl1*
Mutations in Aurora of Drosophila and related Saccharomyces cerevisiae Ipl1 kinase are known to cause abnormal chromosome… 
Highly Cited
1995
Highly Cited
1995
Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase.
Persistent stimulation of the beta 1-adrenergic receptor (beta 1AR) engenders, within minutes, diminished responsiveness of the… 
Highly Cited
1995
Highly Cited
1995
Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C.
With chronic opiate use, opioid receptor desensitization may be one of the important mechanisms underlying the development of… 
Highly Cited
1993
Highly Cited
1993
Constitutively active mutants of the alpha 2-adrenergic receptor.
We have mutated a single residue, Thr373 [corrected], in the C-terminal portion of the third intracellular loop of the alpha 2C10… 
Highly Cited
1987
Highly Cited
1987
Ion activities and potassium uptake mechanisms of glial cells in guinea‐pig olfactory cortex slices.
1. Double‐barrelled ion‐sensitive micro‐electrodes were used to measure changes in the intracellular activities of K+, Na+ and Cl… 
Highly Cited
1986
Highly Cited
1986
K+, Na+, and Cl- activities in ventricular myocytes isolated from rabbit heart.
Intracellular K+, Na+, and Cl- activities (aiK, aiNa and aiCl) were measured in ventricular myocytes enzymatically isolated from… 
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