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Ataxia Telangiectasia

Known as: ATAXIA-TELANGIECTASIA, Louis Bar Syndrome, AT, COMPLEMENTATION GROUP A 
An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (2)

ATAXIA-TELANGIECTASIA-LIKE DISORDERNijmegen Breakage Syndrome
ATM geneATM protein, humanATM wt AlleleATM, 4-BP DEL, IVS20

Broader (3)

Hereditary DiseasesSpinocerebellar DegenerationTelangiectasis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Activation of Ataxia Telangiectasia-mutated DNA Damage Checkpoint Signal Transduction Elicited by Herpes Simplex Virus Infection*
Eukaryotic cells are equipped with machinery to monitor and repair damaged DNA. Herpes simplex virus (HSV) DNA replication occurs… 
Highly Cited
2002
Highly Cited
2002
ATR Is Not Required for p53 Activation but Synergizes with p53 in the Replication Checkpoint*
ATR (ataxiatelangiectasia and Rad-3-related) is a protein kinase required for survival after DNA damage. A critical role for ATR… 
Highly Cited
2001
Highly Cited
2001
Ataxia Telangiectasia Mutated-Dependent Apoptosis after Genotoxic Stress in the Developing Nervous System Is Determined by Cellular Differentiation Status
Ataxia-telangiectasia (A-T) is a neurodegenerative syndrome resulting from dysfunction of ATM (ataxia telangiectasia mutated… 
Highly Cited
1995
Highly Cited
1995
Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells.
Cells derived from individuals with ataxia telangiectasia (AT) show enhanced spontaneous levels of chromosomal abnormalities and… 
Highly Cited
1989
Highly Cited
1989
Testosterone implanted in the preoptic area of male Japanese quail must be aromatized to activate copulation
Highly Cited
1989
Highly Cited
1989
Enhanced tumor localization and in vivo stability of a monoclonal antibody radioiodinated using N-succinimidyl 3-(tri-n-butylstannyl)benzoate.
Loss of radiolabel after in vivo administration of labeled monoclonal antibodies (MAbs) to cancer patients is a likely cause of… 
Highly Cited
1988
Highly Cited
1988
Cancer in homozygotes and heterozygotes of ataxia-telangiectasia and xeroderma pigmentosum in Britain.
We have documented mortality and cancer incidence in the families of 67 patients with ataxia-telangiectasia and 48 patients with… 
Highly Cited
1976
Highly Cited
1976
Defective excision repair of γ-ray-damaged DNA in human (ataxia telangiectasia) fibroblasts
ATAXIA telangiectasia (AT) (Louis–Bar syndrome) is a rare human neurovascular disease displaying an autosomal recessive pattern… 
Highly Cited
1976
Highly Cited
1976
Chemical mutagen hypersensitivity in ataxia telangiectasia
THE growth of knowledge about DNA replication and repair in bacteria has been aided by the availability of a series of mutations… 
Highly Cited
1969
Highly Cited
1969
Immunoglobulin E deficiency in ataxia-telangiectasia.
Abstract An IgE deficiency was demonstrated in 11 of 16 patients with ataxia-telangiectasia. No relation to age or to the level… 
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